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Chinese Optics Letters

Chinese Optics Letters


  • Vol. 5, Iss. 2 — Feb. 10, 2007
  • pp: 105–107

Raman spectroscopy of Chinese human skin in vivo

Yongzeng Li, Rong Chen, Haishan Zeng, Zhiwei Huang, Shangyuan Feng, and Shusen Xie  »View Author Affiliations

Chinese Optics Letters, Vol. 5, Issue 2, pp. 105-107 (2007)

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A novel and compact near-infrared (NIR) Raman system is developed using 785-nm diode laser, volume-phase technology (VPT) holographic system, and NIR intensified charge-coupled device (CCD). Signal-to-noise ratio (SNR) and resolution are improved compared with ordinary acquisition method by a specially designed optical fiber detector and the spectrograph image aberration correction with a parabolic-line fiber array. In 1-5 s, Raman spectra of different parts of Chinese human skin are acquired. Autofluorescence is subtracted from the raw spectrum by polynomial fitting and skin Raman spectrum is then smoothed for further analysis.

© 2007 Chinese Optics Letters

OCIS Codes
(120.4640) Instrumentation, measurement, and metrology : Optical instruments
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(300.6450) Spectroscopy : Spectroscopy, Raman

Yongzeng Li, Rong Chen, Haishan Zeng, Zhiwei Huang, Shangyuan Feng, and Shusen Xie, "Raman spectroscopy of Chinese human skin in vivo," Chin. Opt. Lett. 5, 105-107 (2007)

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  1. S. Fendel and B. Schrader, Fresenius J. Anal. Chem. 360, 609 (1998).
  2. P. J. Caspers, G. W. Lucassen, R. Wolthuis, H. A. Bruining, and G. J. Puppels, Biospectroscopy 4, 31 (1998).
  3. T. R. Hata, T. A. Scholz, I. V. Ermakov, R. W. McClane, F. Khachik, W. Gellermann, and L. K. Pershing, J. Invest. Dermatology 115, 441 (2000).
  4. M. Gniadecka, O. F. Nielsen, and H. C. Wulf, J. Molecular Structure 661-662, 405 (2003).
  5. I. V. Ermakov, M. R. Ermakova, W. Gellermann, and J. Lademann, J. Biomed. Opt. 9, 332 (2004).
  6. J. Yang, J. Guo, L. Wu, Z. Sun, W. Cai, and Z. Wang, Chin. Opt. Lett. 3, 705 (2005).
  7. "In vivo Raman measurements of human skin," http://www.jobinyvon.com/usadvisions/Raman/biology_appnotes.htm.

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