The sensitivity of diffuse optical tomography (DOT) imaging exponentially decreases with the increase of photon penetration depth, which leads to a poor depth resolution for DOT. In this letter, an exponential adjustment method (EAM) based on maximum singular value of layered sensitivity is proposed. Optimal depth resolution can be achieved by compensating the reduced sensitivity in the deep medium. Simulations are performed using a semi-infinite model and the simulation results show that the EAM method can substantially improve the depth resolution of deeply embedded objects in the medium. Consequently, the image quality and the reconstruction accuracy for these objects have been largely improved.
© 2008 Chinese Optics Letters
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6960) Medical optics and biotechnology : Tomography
Haijing Niu, Ping Guo, Xiaodong Song, and Tianzi Jiang, "Improving depth resolution of diffuse optical tomography with an exponential adjustment method based on maximum singular value of layered sensitivity," Chin. Opt. Lett. 6, 886-888 (2008)