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Chinese Optics Letters

Chinese Optics Letters

| PUBLISHED MONTHLY BY CHINESE LASER PRESS AND DISTRIBUTED BY OSA

  • Editor: Zhizhan Xu
  • Vol. 11, Iss. 7 — Jul. 1, 2013
  • pp: 072201–

Direct fabrication of a microfluidic chip for electrophoresis analysis by water-assisted femtosecond laser writing in porous glass

Yongfeng Ju, Changning Liu, Yang Liao, Yang Liu, Long Zhang, Yinglong Shen, Danping Chen, and Ya Cheng  »View Author Affiliations


Chinese Optics Letters, Vol. 11, Issue 7, pp. 072201- (2013)


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Abstract

We report the direct fabrication of a microfluidic chip composed of two high-aspect ratio microfluidic channels with lengths of 3.5 cm and 8 mm in a glass substrate by femtosecond laser micromachining. The fabrication mainly consists of two steps: 1) writing microchannels and microchambers in a porous glass by scanning a tightly focused laser beam; 2) high-temperature annealing of the glass sample to collapse all the nanopores in the glass. Migration of derivatized amino acids is observed in the microfluidic channel by applying electric voltage across the long-migration microchannel.

© 2013 Chinese Optics Letters

OCIS Codes
(220.4000) Optical design and fabrication : Microstructure fabrication
(230.4000) Optical devices : Microstructure fabrication

ToC Category:
Optical Design and Fabrication

Citation
Yongfeng Ju, Changning Liu, Yang Liao, Yang Liu, Long Zhang, Yinglong Shen, Danping Chen, and Ya Cheng, "Direct fabrication of a microfluidic chip for electrophoresis analysis by water-assisted femtosecond laser writing in porous glass," Chin. Opt. Lett. 11, 072201- (2013)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-11-7-072201


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References

  1. G. M. Whitesides, Nature 442, 368 (2006).
  2. A. Manz, N. Graber, and H. M. Widmer, Sens. Actuators B1, 244 (1990).
  3. B.-H. Jo, L. M. V. Lerberghe, K. M. Motsegood, and D. J. Beebe, J. Microelectromech. Syst. 9, 76 (2000).
  4. M. S. Giridhar, K. Seong, A. Schuzgen, P. Khulbe, N. Peyghambarian, and M. Mansuripur, Appl. Opt. 43, 4584 (2004).
  5. Y. Li, X. Gao, M. Jiang, Q. Sun, and J. Tian, Chin. Opt. Lett. 10, 102201 (2012).
  6. Y. Li, K. Itoh, W. Watanabe, K. Yamada, D. Kuroda, J. Nishii, and Y. Jiang, Opt. Lett. 26, 1912 (2001).
  7. A. Marcinkevicius, S. Juodkazis, M. Watanabe, M. Miwa, S. Matsuo, H. Misawa, and J. Nishii, Opt. Lett. 26, 277 (2001).
  8. D. J. Hwang, T. Y. Choi, and C. P. Grigoropoulos, Appl. Phys. A Mater. Sci. Process. 79, 605 (2004).
  9. K. Sugioka, M. Masuda, T. Hongo, Y. Cheng, K. Shihoyama, and K. Midorikawa, Appl. Phys. A Mater. Sci. Process. 79, 815 (2004).
  10. Y. Cheng, K. Sugioka, and K. Midorikawa, Appl Surf. Sci. 248, 172 (2005).
  11. R. An, Y. Li, Y. Dou, D. Liu, H. Yang, and Q. Gong, Appl. Phys. A Mater. Sci. Process. 83, 27 (2006).
  12. F. He, Y. Cheng, Z. Xu, Y. Liao, J. Xu, H. Sun, C. Wang, Z. Zhou, K. Sugioka, K. Midorikawa, Y. Xu, and X. Chen, Opt. Lett. 35, 282 (2010).
  13. Y. Wu, C.-Y. Wang, W. Jia, X. Ni, M. Hu, and L. Chai, Chin. Opt. Lett. 6, 51 (2008).
  14. Y. Liao, Y. Ju, L. Zhang, F. He, Q. Zhang, Y. Shen, D. Chen, Y. Cheng, Z. Xu, K. Sugioka, and K. Midorikawa, Opt. Lett. 35, 3225 (2010).
  15. Y. Ju, Y. Liao, L. Zhang, Y. Sheng, Q. Zhang, D. Chen, Y. Cheng, Z. Xu, K. Sugioka, and K. Midorikawa, Microfluidics and Nanofluidics 11, 111 (2011).
  16. Y. Liao, J. Song, E. Li, Y. Luo, Y. Shen, D. Chen, Y. Cheng, Z. Xu, K. Sugioka, and K. Midorikawa, Lab on a Chip 12, 746 (2012).
  17. Y. Liao, Y. Shen, L. Qiao, D. Chen, Y. Cheng, K. Sugioka, and K. Midorikawa, Opt. Lett. 38, 187 (2013).
  18. Y. Liao, J. Xu, H. Sun, J. Song, X. Wang, and Y. Cheng, Appl. Surf. Sci. 254, 7018 (2008).
  19. K. Sugioka and Y. Cheng, Lab on a Chip 12, 3576 (2012).
  20. C. Dongre, J. van Weerd, N. Bellini, R. Osellame, G. Cerullo, R. van Weeghel, H. J. W. M. Hoekstra, and M. Pollnau, Biomed. Opt. Express 1, 729 (2010).
  21. D. Chen, H. Miyoshi, T. Akai, and T. Yazawa, Appl. Phys. Lett. 86, 231908 (2005).

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