A possible correlation between second-order dispersion and glucose concentration is presented for the first time. The second-order dispersions of three different glucose concentrations: hypoglycemia, normal level, and hyperglycemia are analyzed over the wavelength range from 0.55 to 0.8 micron by Fourier analysis of the interferogram. The preliminary correlation between second-order dispersion and glucose concentration is investigated by linear fitting the second-order dispersion from 0.65 to 0.75 micron. This correlation is expected to determine the different glucose concentrations by measuring the second-order dispersion, which can be considered as a potentially noninvasive method to measure glucose concentration in human eye.
© 2005 Chinese Optics Letters
(120.3930) Instrumentation, measurement, and metrology : Metrological instrumentation
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
Juan Liu, Shangqi Wang, Morteza Bagherzadeh, Adolf Friedrich Fercher, and Shuisheng Jian, "Possible correlation between second-order dispersion and glucose concentration investigated by low time-coherence interferometry," Chin. Opt. Lett. 3, S91-S93 (2005)