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Chinese Optics Letters

Chinese Optics Letters

| PUBLISHED MONTHLY BY CHINESE LASER PRESS AND DISTRIBUTED BY OSA

  • Vol. 3, Iss. 12 — Dec. 10, 2005
  • pp: 705–707

Raman spectroscopic identification of normal and malignant human stomach cells

Jipeng Yang, Jianyu Guo, Liangping Wu, Zhenrong Sun, Weiying Cai, and Zugeng Wang  »View Author Affiliations


Chinese Optics Letters, Vol. 3, Issue 12, pp. 705-707 (2005)


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Abstract

Micro-Raman spectroscopy is employed to identify the normal and malignant human stomach cells. For the cancer cell, the reduced intensity of the Raman peak at 1250 cm^(-1) indicates that the protein secondary structure transforms from ?-sheet or disordered structures to ?-helical, while the increased intensity of the symmetric PO2 stretching vibration mode at 1094 cm^(-1) shows the increased DNA content. The ratio of the intensity at 1315 cm^(-1) to that at 1340 cm^(-1) reduces from 1.8 for the normal cell to 1.1 for the cancer cell in the course of canceration, and the ratio of the intensity at 1655 cm^(-1) to that at 1450 cm^(-1) increases from 1.00 for the cancer cell to 1.26 for the normal cell which indicates that the canceration of stomach cell may induce saturation of the lipid chain.

© 2005 Chinese Optics Letters

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1530) Medical optics and biotechnology : Cell analysis
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(300.6450) Spectroscopy : Spectroscopy, Raman

Citation
Jipeng Yang, Jianyu Guo, Liangping Wu, Zhenrong Sun, Weiying Cai, and Zugeng Wang, "Raman spectroscopic identification of normal and malignant human stomach cells," Chin. Opt. Lett. 3, 705-707 (2005)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-3-12-705


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References

  1. Z. P. Wang, H. X. Han, and G. H. Li, Chin. J. Light Scattering (in Chinese) 11, 398 (2000).
  2. X. L. Yan, Q. G. Wang, R. X. Dong, Z. X. Sun, and P. H. Xiu, Spectrosc. Spect. Anal. (in Chinese) 23, 1129 (2003).
  3. S. R. Hawi, W. B. Campbell, A. Kajdacsy-Balla, R. Murphy, F. Adar, and K. Nithipatikom, Cancer Lett. 110, 35 (1996).
  4. R. Manoharan, Y. Wang, and M. S. Feld, Spectrochimica Acta Part A 52, 215 (1996).
  5. D. Pappas and B. W. Smith, J. D. Winefordner, Talanta 51, 131 (2000).
  6. B. Rigas and P. T. T. Wong, Cancer Research 52, 84 (1992).
  7. H. Huo, X. Hu, H. W. Guan, X. F. Wang, X. Che, and W. D. Huang, Chemical Journal of Chinese Universities (in Chinese) 21, 1244 (2000).
  8. Q. B. Li, X. J. Sun, Y. Z. Xu, L. M. Yang, Y. F. Zhang, S. F. Weng, J. S. Shi, and J. G. Wu, Clinical Chemistry 51, 346 (2005).
  9. N. Fujioka, Y. Morimoto, T. Arai, and M. Kikuchi, Cancer Detection and Prevention 28, 32 (2004).
  10. Y. P. Dong and Y. W. Lin, Spectrosc. Spect. Anal. (in Chinese) 21, 324 (2001).
  11. R. Wood, M. A. Quinn, F. R. Burden, and D. Mcnaughton, Biospectroscopy 2, 143 (1996).
  12. P. T. T. Wong, S. M. Goldstein, R. C. Grekin, T. A. Godwin, C. Pivik, and B. Rigas, Cancer Research 53, 762 (1993).
  13. P. V. Huong, Vibrational Spectroscopy 11, 17 (1996).
  14. A. Mizuno, H. Kitajima, K. Kawauchi, S. Muraishi, and Y. Ozaki, Journal of Raman Spectroscopy 25, 25 (1994).
  15. R. R. Alfano, C. H. Liu, W. L. Sha, H. R. Zhu, D. L. Akins, J. Cleary, R. Prudente, and E. Cellmer, Lasers in the Life Sciences 4, 23 (1991).
  16. M. G. Shim, L. K. S. Wong, N. E. Marcon, and B. C. Wilson, Photochem. Photobiol. 72, 146 (2000).
  17. A. Mahadevan-Jansen, M. F. Mitchell, N. Ramanujam, A. Malpica, S. Thomsen, U. Utzinger, and R. Richards-Kortum, Photochem. Photobiol. 68, 123 (1998).
  18. N. Stone, P. Stavroulaki, C. Kendall, M. Birchall, and H. Barr, The Laryngoscope 110, 1756 (2000).
  19. M. Gniadecka, H. Wulf, O. Nielsen, D. Christensen, and J. Hercogova, Photochem. Photobiol. 66, 418 (1997).
  20. M. Grube, J. R. Gapes, and K. C. Schuster, Analytica Chimica Acta 471, 127 (2002).
  21. X. F. Ling, W. H. Li, Y. Y. Song, Z. L. Yang, Y. Z. Xu, S. P. Weng, Z. Xu, X. B. Fu, X. S. Zhou, and J. G. Wu, Spectrosc. Spect. Anal. (in Chinese) 20, 692 (2000).
  22. W. Y. Tang, J. F. Wang, and P. Xu, Laser Journal (in Chinese) 25, 82 (2004).

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