OSA's Digital Library

Chinese Optics Letters

Chinese Optics Letters


  • Vol. 3, Iss. 5 — May. 10, 2005
  • pp: 289–291

Effects of different levels of vitamin C on UV radiation-induced DNA damage

Dianfeng Zhou, Hang Heng, Kang Ji, and Weizhong Ke  »View Author Affiliations

Chinese Optics Letters, Vol. 3, Issue 5, pp. 289-291 (2005)

View Full Text Article

Acrobat PDF (247 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

  • Export Citation/Save Click for help


The Raman spectra of DNA in different levels of vitamin C with 10- and 30-min ultraviolet (UV) radiations were reported. The intensity of UV radiation was 18.68 W/m2. The experimental results proved that vitamin C could alone prevent UV radiation from damaging DNA, but the effects depended on the concentration of vitamin C. When the concentration of vitamin C was about 0.08-0.4 mmol/L, vitamin C decreased UV radiation-induced DNA's damage. When the concentration of vitamin C exceeded 0.4 mmol/L, vitamin C accelerated DNA's damage instead. Maybe the reason is that when DNA in aqueous solution is radiated by UV, free radicals come into being, and vitamin C can scavenge free radicals, so vitamin C in lower concentration can protect DNA. The quantity of free radicals is finite, when vitamin C is superfluous, free radicals have been scavenged absolutely and vitamin C is residual. Vitamin C is a strong reductant. When the mixture of DNA and residual vitamin C is radiated by UV, vitamin C reacts with DNA. The more residual vitamin C and the longer time of UV radiation, the more DNA is damaged.

© 2005 Chinese Optics Letters

OCIS Codes
(300.6170) Spectroscopy : Spectra
(300.6390) Spectroscopy : Spectroscopy, molecular
(300.6450) Spectroscopy : Spectroscopy, Raman

Dianfeng Zhou, Hang Heng, Kang Ji, and Weizhong Ke, "Effects of different levels of vitamin C on UV radiation-induced DNA damage," Chin. Opt. Lett. 3, 289-291 (2005)

Sort:  Author  |  Year  |  Journal  |  Reset


  1. J. Li, Y. Liu, W. Sun, and M. Cheng, Chin. J. Public Health (in Chinese) 22, 177 (2004).
  2. P. Moller, M. Viscovich, J. Lykkesfeldt, S. Loft, A. Jensen, and H. E. Polusen, Eur. J. Nutr. 43, 1 (2004).
  3. D. Zhou and W. Ke, Spectroscopy and Spectral Analysis 24, 1370 (2004).
  4. W. Ke, D. Yu, and J. Wu, Spectrochimica Acta Part A 55, 1081 (1999).
  5. C. Jiang, Z. Zeng, and Q. Zhang, Hygiene Fascicule of Overseas Physic (in Chinese) 26, 147 (1999).
  6. F. Yu, Hygiene Fascicule of Overseas Physic (in Chinese) 29, 141 (2002).
  7. H. Zhao, Y. Yu, and Z. Zhang, Chin. Science Bulletin (in Chinese) 43, 955 (1998).

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited