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Chinese Optics Letters

Chinese Optics Letters

| PUBLISHED MONTHLY BY CHINESE LASER PRESS AND DISTRIBUTED BY OSA

  • Vol. 3, Iss. S1 — Aug. 28, 2005
  • pp: S173–S175

Fluorescence detection system and laminate-based disposable microfluidic chip

Rudi Irawan, Swee Chuan Tjin, Dianwen Zhang, and Xiaoqin Fang  »View Author Affiliations


Chinese Optics Letters, Vol. 3, Issue S1, pp. S173-S175 (2005)


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Abstract

Development of a compact fluorescence point-of-care system (POCS) is challenging. A prototype of compact fluorescence detection system and disposable microfluidic chip reported in this letter used a blue LED, 600-micron fiber, CCD detector, mylar and polymethyl-methacrylate (PMMA), and fluorescein solution as an excitation source, light-guide, detector, microfluidic chip substrates and samples, respectively. The results show the system is able to detect 0.01-1000 micro-g/l fluorescein in tris buffered saline pH 8.0 and gives linear response. This prototype can be used as a platform to develop a simple and compact multichannel-fluorescence point-of-care bioassay system with an inexpensive and disposable microfluidic chip.

© 2005 Chinese Optics Letters

OCIS Codes
(120.1880) Instrumentation, measurement, and metrology : Detection
(160.5470) Materials : Polymers
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

Citation
Rudi Irawan, Swee Chuan Tjin, Dianwen Zhang, and Xiaoqin Fang, "Fluorescence detection system and laminate-based disposable microfluidic chip," Chin. Opt. Lett. 3, S173-S175 (2005)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-3-S1-S173

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