A calibration method for optical trap force by use of electrokinetic phenomena
Chinese Optics Letters, Vol. 4, Issue 9, pp. 529-531 (2006)
Acrobat PDF (172 KB)
Abstract
An experimental method for calibration of optical trap force upon cells by use of electrokinetic phenomena is demonstrated. An electronkinetic sample chamber system (ESCS) is designed instead of a common sample chamber and a costly automatism stage, thus the experimental setup is simpler and cheaper. Experiments indicate that the range of the trap force measured by this method is piconewton and sub-piconewton, which makes it fit for study on non-damage interaction between light and biological particles with optical tweezers especially. Since this method is relevant to particle electric charge, by applying an alternating electric field, the new method may overcome the problem of correcting drag force and allow us to measure simultaneously optical trap stiffness and particle electric charge.
© 2006 Chinese Optics Letters
OCIS Codes
(170.1530) Medical optics and biotechnology : Cell analysis
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(200.4880) Optics in computing : Optomechanics
Citation
Youli Yu, Zhenxi Zhang, and Xiaolin Zhang, "A calibration method for optical trap force by use of electrokinetic phenomena," Chin. Opt. Lett. 4, 529-531 (2006)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-4-9-529
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Orientation-independent differential interference contrast microscopy (AO)
- New algorithm and system for measuring size distribution of blood cells (COL)
- Simultaneous manipulation and detection of living cell membrane dynamics (OL)
- Microscope-based label-free microfluidic cytometry (OE)
- Chemical visualization of individual chondrocytes in articular cartilage by attenuated-total-reflection Fourier Transform Infrared Microimaging (BOE)
Related Conference Papers
- Cellular Sorting with Femtoliter Fluid Displacement for Integrated Flow Cytometry Systems
- In vivo Monitoring of Two Circulating Cell Lines Using Two-Color Two-Photon Cytometry
- Whole Spectrum Fluorescence Detection with Ultrafast White Light Excitation
- Drug response measurements using optical forces
- Medical Imaging Systems Using Bio-Inspired Fluidic Lenses
« Previous Article | Next Article »
OSA is a member of 