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Chinese Optics Letters

Chinese Optics Letters

| PUBLISHED MONTHLY BY CHINESE LASER PRESS AND DISTRIBUTED BY OSA

  • Vol. 5, Iss. 8 — Aug. 10, 2007
  • pp: 475–476

Feasibility of photoacoustic tomography for ophthalmology

Tao Lu, Zhiyuan Song, Yixiong Su, Fan Zhang, and Jianquan Yao  »View Author Affiliations


Chinese Optics Letters, Vol. 5, Issue 8, pp. 475-476 (2007)


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Abstract

For the eyeball composed of membrane and liquid, the contrast of ultrasound imaging is not high due to its small variance in acoustic impedance. As a new imaging modality, photoacoustic tomography combines the advantages of pure optical and ultrasonic imaging together and can provide high resolution, high contrast images. In this paper, the feasibility of photoacoustic tomography for ophthalmology is studied experimentally. A Q-switched Nd:YAG pulsed laser with 7-ns pulse width is used to generate photoacoustic signal of a porcine eyeball in vitro. The two-dimensional (2D) optical absorption image of the entire eyeball is reconstructed by time-domain spherical back projection algorithm. The imaging results agree well with the histological structure of the eyeball and show a high imaging contrast.

© 2007 Chinese Optics Letters

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

Citation
Tao Lu, Zhiyuan Song, Yixiong Su, Fan Zhang, and Jianquan Yao, "Feasibility of photoacoustic tomography for ophthalmology," Chin. Opt. Lett. 5, 475-476 (2007)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-5-8-475

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