Different types of femtosecond optical tweezers have become a powerful tool in the modern biological field. However, how to control the irregular targets, including biological cells, using femtosecond optical tweezers remains to be explored. In this study, human red blood cells (hRBCs) are manipulated with femtosecond optical tweezers, and their states under different laser powers are investigated. The results indicate that optical potential traps only can capture the edge of hRBCs under the laser power from 1.4 to 2.8 mW, while it can make hRBCs turn over with the laser power more than 2.8 mW. It is suggested that femtosecond optical tweezers could not only manipulate biological cells, but also subtly control its states by adjusting the laser power.
© 2008 Chinese Optics Letters
(120.4820) Instrumentation, measurement, and metrology : Optical systems
(170.4520) Medical optics and biotechnology : Optical confinement and manipulation
(350.4855) Other areas of optics : Optical tweezers or optical manipulation
Ming Zhou, Haifeng Yang, Jianke Di, and Enlan Zhao, "Manipulation on human red blood cells with femtosecond optical tweezers," Chin. Opt. Lett. 6, 919-921 (2008)