OSA's Digital Library

Chinese Optics Letters

Chinese Optics Letters


  • Vol. 6, Iss. 12 — Dec. 1, 2008
  • pp: 919–921

Manipulation on human red blood cells with femtosecond optical tweezers

Ming Zhou, Haifeng Yang, Jianke Di, and Enlan Zhao  »View Author Affiliations

Chinese Optics Letters, Vol. 6, Issue 12, pp. 919-921 (2008)

View Full Text Article

Acrobat PDF (1490 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

  • Export Citation/Save Click for help


Different types of femtosecond optical tweezers have become a powerful tool in the modern biological field. However, how to control the irregular targets, including biological cells, using femtosecond optical tweezers remains to be explored. In this study, human red blood cells (hRBCs) are manipulated with femtosecond optical tweezers, and their states under different laser powers are investigated. The results indicate that optical potential traps only can capture the edge of hRBCs under the laser power from 1.4 to 2.8 mW, while it can make hRBCs turn over with the laser power more than 2.8 mW. It is suggested that femtosecond optical tweezers could not only manipulate biological cells, but also subtly control its states by adjusting the laser power.

© 2008 Chinese Optics Letters

OCIS Codes
(120.4820) Instrumentation, measurement, and metrology : Optical systems
(170.4520) Medical optics and biotechnology : Optical confinement and manipulation
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

Ming Zhou, Haifeng Yang, Jianke Di, and Enlan Zhao, "Manipulation on human red blood cells with femtosecond optical tweezers," Chin. Opt. Lett. 6, 919-921 (2008)

Sort:  Author  |  Year  |  Journal  |  Reset


  1. A. Ashkin, J. M. Dziedzic, J. E. Bjorkholm, and S. Chu, Opt. Lett. 11, 288 (1986).
  2. X. Meng, Y. Li, S. Zhang, Z. Zhang, and N. Zhao, Chinese J. Lasers B 11, 393 (2002).
  3. J. Andilla, E. Martín-Badosa, and S. Vallmitjana, Opt. Commun. 281, 3786 (2008).
  4. H. Zhang and K.-K. Liu, J. R. Soc. Interface 5, 671 (2008).
  5. H. Mushfique, J. Leach, H. Yin, R. Di Leonardo, M. J. Padgett, and J. M. Cooper, Anal. Chem. 80, 4237 (2008).
  6. F. He and Y. Cheng, Chinese J. Lasers (in Chinese) 34, 595 (2007).
  7. Z. Han, C. Zhou, and E. Dai, Chinese J. Lasers (in Chinese) 34, 715 (2007).
  8. G. Wang and Z. Zheng, Chinese J. Lasers (in Chinese) 35, 524 (2008).
  9. Y. Wu, C.-Y. Wang, W. Jia, X. Ni, M. Hu, and L. Chai, Chin. Opt. Lett. 6, 51 (2008).
  10. X. Hu, J. Song, Q. Zhou, L. Yang, X. Wang, C. Zhu, and J. Qiu, Chin. Opt. Lett. 6, 388 (2008).
  11. B. Agate, C. T. A. Brown, W. Sibbett, and K. Dholakia, Opt. Express 12, 3011 (2004).
  12. H. Little, C. T. A. Brown, V. Garcés-Chávez, W. Sibbett, and K. Dholakia, Opt. Express 12, 2560 (2004).
  13. N. K. Metzger, E. M. Wright, W. Sibbett, and K. Dholakia, Opt. Express 14, 3677 (2006).
  14. D. Morrish, X. Gan, and M. Gu, Opt. Express 12, 4198 (2004).
  15. K.-B. Im, S. Han, H. Park, D. Jin, S.-K. Kim, and B.-M. Kim, Proc. SPIE 5699, 274 (2005).
  16. K.-B. Im, S.-B. Ju, S. Han, H. Park, B.-M. Kim, D. Jin, and S.-K. Kim, J. Korean Phys. Soc. 48, 968 (2006).
  17. Q. Xing, F. Mao, L. Chai, and Q. Wang, Opt. Laser Technol. 36, 635 (2004).
  18. M. Dao, C. T. Lim, and S. Suresh, J. Mech. Phys. Solids 51, 2259 (2003).
  19. U. Morgner, F. X. Katner, S. H. Cho, Y. Chen, H. A. Haus, J. G. Fujimoto, E. P. Ippen, V. Scheuer, G. Angelow, and T. Tschudi, Opt. Lett. 24, 411 (1999).
  20. Z. Jiang, D. Yuan, R. Chen, W. Huang, J. Chu, and Y. Liu, Microfabrication Technology (in Chinese) (2) 59 (2003).

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited