A novel structure of fiber optic biosensor and its principle are introduced. The sample is detected in microchannels of several microns diameter in fiber optic biosensors. The relation between the optic fiber tapered angle and the fluorescence incident angle is calculated in signal receiving part. As the sensor is a zero-order system, calculating formula of the static sensitivity is derived. When ZnSe nano-crystalline cluster is used for marking the molecules, the static sensitivity for fiber optic biosensors is calculated. At the same time, the relation between the static sensitivity and the ratio of exciting wavelength to fluorescence wavelength is presented.
© 2008 Chinese Optics Letters
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(160.2540) Materials : Fluorescent and luminescent materials
(350.3950) Other areas of optics : Micro-optics
(280.1415) Remote sensing and sensors : Biological sensing and sensors
Zhongchen Bai, Shuijie Qin, Jing Li, Dashun Huang, and Xin Zhang, "Static sensitivity calculation of a novel fiber optic biosensor," Chin. Opt. Lett. 6, 922-924 (2008)