Inactivation of bovine immunodeficiency virus by photodynamic therapy with HMME
Chinese Optics Letters, Vol. 6, Issue 12, pp. 944-946 (2008)
Acrobat PDF (206 KB)
Abstract
To investigate the effect of photodynamic therapy (PDT) with hematoporphrin monomethyl ether (HMME) on bovine immunodeficiency virus (BIV) can provide the basis theory for photoinactivation of human immunodeficiency virus (HIV). To assess the protection of HMME-PDT on the cell line Cf2Th infected with BIVR29 by 3-(4,5)-dimethylthiahiazol-2-y1-3,5-di-phenytetrazolium bromide (MTT) with power density of 5 and 25 mW/cm2 and energy density from 0.6 to 3 J/cm2. To observe the inhibition of membrane fusion using a new reporter cell line BIVE by fluorescence microscope. HMME-PDT has significant protectant effects on Cf2Th-BIVR29 with both power densities, especially in the group of high power density. Fluorescent microscope shows that there is no significant difference between the group of PDT and control, which means PDT could not inhibit the BIV-mediated membrane fusion.
© 2008 Chinese Optics Letters
OCIS Codes
(170.1530) Medical optics and biotechnology : Cell analysis
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.5180) Medical optics and biotechnology : Photodynamic therapy
Citation
Huijuan Yin, Yingxin Li, Zhaohui Zou, Wentao Qiao, Xue Yao, Yang Su, and Hongyan Guo, "Inactivation of bovine immunodeficiency virus by photodynamic therapy with HMME," Chin. Opt. Lett. 6, 944-946 (2008)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-6-12-944
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Confocal fluorescence spectroscopy and anisotropy imaging system (OL)
- Femtosecond laser disruption of subcellular organelles in a living cell (OE)
- Fluorescence correlation microscopy with real-time alignment readout (AO)
- Portable in situ fluorescence cytometry of microscale cell-based assays (OL)
- Investigation of photodynamic therapy on streptococcus mutans of oral biofilm (COL)
Related Conference Papers
- Effects of fixation on cyan fluorescent protein and its fluorescence resonance energy transfer efficiency
- Photodynamic Tumor Vascular Targeting Enhances Cancer Chemotherapy
- Photodynamic Tumor Vascular Targeting Enhances Cancer Chemotherapy
- Photodynamic Tumor Vascular Targeting Enhances Cancer Chemotherapy
- Photodynamic Tumor Vascular Targeting Enhances Cancer Chemotherapy
« Previous Article | Next Article »
OSA is a member of 