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Chinese Optics Letters

Chinese Optics Letters

| PUBLISHED MONTHLY BY CHINESE LASER PRESS AND DISTRIBUTED BY OSA

  • Vol. 8, Iss. 1 — Jan. 1, 2010
  • pp: 86–88

Detection system for singlet oxygen luminescence in photodynamic therapy

Buhong Li, Huiyun Lin, Defu Chen, Min Wang, and Shusen Xie  »View Author Affiliations


Chinese Optics Letters, Vol. 8, Issue 1, pp. 86-88 (2010)


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Abstract

Singlet oxygen (1O2) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of 1O2 near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved 1O2 luminescence spectra. The triplet state and 1O2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in 1O2 luminescence-based PDT dosimetry.

© 2010 Chinese Optics Letters

OCIS Codes
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.5180) Medical optics and biotechnology : Photodynamic therapy
(300.6280) Spectroscopy : Spectroscopy, fluorescence and luminescence

Citation
Buhong Li, Huiyun Lin, Defu Chen, Min Wang, and Shusen Xie, "Detection system for singlet oxygen luminescence in photodynamic therapy," Chin. Opt. Lett. 8, 86-88 (2010)
http://www.opticsinfobase.org/col/abstract.cfm?URI=col-8-1-86


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