We demonstrate the subsurface imaging of an articular cartilage using Fourier-domain common-path optical coherence tomography. The bare fiber probe integrated with a hypodermic needle provides the rigidness required to perform lateral scanning with less microscale bending. By submerging both the probe and the specimen into saline solution, we not only reduce the beam divergence, but also increase the signal-to-noise ratio compared with the measurement in free space. Our system can dierentiate the characteristic cartilage zones and identity various micro-structured defects in an ex vivo chicken knee cartilage, thus demonstrating that it could be used to conduct early arthritis diagnosis and intraoperative endo-microscopy.
© 2010 Chinese Optics Letters
(030.1670) Coherence and statistical optics : Coherent optical effects
(060.2310) Fiber optics and optical communications : Fiber optics
(110.4500) Imaging systems : Optical coherence tomography
(170.0110) Medical optics and biotechnology : Imaging systems
Jae-Ho Han, Xuan Liu, Jin U. Kang, and Chul Gyu Song, "High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography," Chin. Opt. Lett. 8, 167-169 (2010)