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Journal of the Optical Society of America A

Journal of the Optical Society of America A


  • Vol. 18, Iss. 4 — Apr. 1, 2001
  • pp: 932–939

Corrections for inhomogeneities in biological tissue caused by blood vessels

Anne Talsma, Britton Chance, and Reindert Graaff  »View Author Affiliations

JOSA A, Vol. 18, Issue 4, pp. 932-939 (2001)

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In tissue optics, the assumption that blood is homogeneously distributed in tissue can give rise to miscalculations because blood is found only in blood vessels. In our paper randomly oriented blood vessels are treated as particles for which we obtained apparent absorption and scattering coefficients by means of the Monte Carlo method. Apart from this correction for the contribution of blood properties in tissue, a correction for the contribution of the surrounding tissue proved to be needed as well. The results found with our model were compared with available results from the literature.

© 2001 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.5280) Medical optics and biotechnology : Photon migration
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.7050) Medical optics and biotechnology : Turbid media

Original Manuscript: March 1, 2000
Revised Manuscript: September 14, 2000
Manuscript Accepted: October 19, 2000
Published: April 1, 2001

Anne Talsma, Britton Chance, and Reindert Graaff, "Corrections for inhomogeneities in biological tissue caused by blood vessels," J. Opt. Soc. Am. A 18, 932-939 (2001)

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