OSA's Digital Library

Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Editor: Franco Gori
  • Vol. 31, Iss. 7 — Jul. 1, 2014
  • pp: 1520–1530

Rapid computation of the amplitude and phase of tightly focused optical fields distorted by scattering particles

Janaka C. Ranasinghesagara, Carole K. Hayakawa, Mitchell A. Davis, Andrew K. Dunn, Eric O. Potma, and Vasan Venugopalan  »View Author Affiliations


JOSA A, Vol. 31, Issue 7, pp. 1520-1530 (2014)
http://dx.doi.org/10.1364/JOSAA.31.001520


View Full Text Article

Enhanced HTML    Acrobat PDF (1688 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We develop an efficient method for accurately calculating the electric field of tightly focused laser beams in the presence of specific configurations of microscopic scatterers. This Huygens–Fresnel wave-based electric field superposition (HF-WEFS) method computes the amplitude and phase of the scattered electric field in excellent agreement with finite difference time-domain (FDTD) solutions of Maxwell’s equations. Our HF-WEFS implementation is 2–4 orders of magnitude faster than the FDTD method and enables systematic investigations of the effects of scatterer size and configuration on the focal field. We demonstrate the power of the new HF-WEFS approach by mapping several metrics of focal field distortion as a function of scatterer position. This analysis shows that the maximum focal field distortion occurs for single scatterers placed below the focal plane with an offset from the optical axis. The HF-WEFS method represents an important first step toward the development of a computational model of laser-scanning microscopy of thick cellular/tissue specimens.

© 2014 Optical Society of America

OCIS Codes
(170.0180) Medical optics and biotechnology : Microscopy
(260.1960) Physical optics : Diffraction theory
(290.7050) Scattering : Turbid media

ToC Category:
Scattering

History
Original Manuscript: January 14, 2014
Revised Manuscript: April 28, 2014
Manuscript Accepted: May 7, 2014
Published: June 18, 2014

Virtual Issues
Vol. 9, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Janaka C. Ranasinghesagara, Carole K. Hayakawa, Mitchell A. Davis, Andrew K. Dunn, Eric O. Potma, and Vasan Venugopalan, "Rapid computation of the amplitude and phase of tightly focused optical fields distorted by scattering particles," J. Opt. Soc. Am. A 31, 1520-1530 (2014)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-31-7-1520

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited