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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 11, Iss. 7 — Jul. 1, 1994
  • pp: 1958–1969

Foveal flicker sensitivity in healthy aging eyes. II. Cross-sectional aging trends from 18 through 77 years of age

Charlene B. Y. Kim and Melanie J. Mayer  »View Author Affiliations


JOSA A, Vol. 11, Issue 7, pp. 1958-1969 (1994)
http://dx.doi.org/10.1364/JOSAA.11.001958


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Abstract

Foveal flicker contrast sensitivity was measured for healthy adults at temporal frequencies from 2.5 to 50 Hz. The first experiment compared two-interval forced-choice (2IFC) and yes-no detection (Y–N) testing procedures for younger (19–33-year-old) and older (67–73-year-old) observers. The 2IFC technique resulted in higher absolute estimates of sensitivity. However, within a method, relative differences were similar. Therefore the two methods gave similar estimates of temporal contrast-sensitivity change with age. Experiment 2 compared 89 observers from 18 through 77 years of age to explore the effect of the time course of aging on flicker sensitivity. The 2IFC procedure was used, and retinal illuminance changes with age were controlled. Significant overall losses in contrast sensitivity were found for the 45–54, 55–64, and 65–77-year-old age groups. Overall sensitivities for the 35–44-year-old group were comparable with or (not significantly) higher than those for the 18–24- and 25–34-year-old groups. The results suggested that (1) foveal temporal contrast sensitivity does not decline until after 44 years, (2) losses after 44 years are in amplitude but not in temporal resolution of the visual response, and (3) the mean rate of loss is ∼0.78 decilog per decade after 44 years. These results are consistent with the existence of three phases of development of temporal contrast sensitivity over the life span. The results also emphasize the importance of including healthy-eyed age-matched controls in studies of flicker sensitivity in visual dysfunctions that affect mainly older adults.

© 1994 Optical Society of America

History
Original Manuscript: December 9, 1992
Revised Manuscript: February 15, 1994
Manuscript Accepted: February 18, 1994
Published: July 1, 1994

Citation
Charlene B. Y. Kim and Melanie J. Mayer, "Foveal flicker sensitivity in healthy aging eyes. II. Cross-sectional aging trends from 18 through 77 years of age," J. Opt. Soc. Am. A 11, 1958-1969 (1994)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-11-7-1958


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References

  1. M. J. Mayer, C. B. Y. Kim, A. Svingos, A. Glucs, “Foveal flicker sensitivity in healthy aging eyes. I. Compensating for pupil variation,” J. Opt. Soc. Am. A 5, 2201–2209 (1988). [CrossRef] [PubMed]
  2. C. E. Wright, N. Drasdo, “The influence of age on the spatial and temporal contrast sensitivity function,” Doc. Ophthalmol. 59, 385–395 (1985). [CrossRef] [PubMed]
  3. C. W. Tyler, “Two processes control variations in flicker sensitivity over the life span,” J. Opt. Soc. Am. A 6, 481–490 (1989). [CrossRef] [PubMed]
  4. J. Botwinick, “Cautiousness in advanced age,” J. Gerontol. 21, 347–353 (1966). [CrossRef] [PubMed]
  5. M. A. Okun, “Adult age and cautiousness in decision,” Hum. Dev. 19, 220–233 (1976). [CrossRef]
  6. R. A. Weale, The Aging Eye (Lewis, London, 1963).
  7. R. D. Gunkel, P. Gouras, “Changes in scotopic visibility thresholds with age,” Arch. Ophthalmol. 69, 4–9 (1963). [CrossRef] [PubMed]
  8. D. V. Norren, J. J. Vos, “Spectral transmission of the human ocular media,” Vision Res. 14, 1237–1244 (1974). [CrossRef] [PubMed]
  9. J. Sigelman, S. L. Trokel, A. Spector, “Quantitative biomicroscopy of lens light back scatter,” Arch. Ophthalmol. 92, 437–442 (1974). [CrossRef] [PubMed]
  10. A. Spector, S. Li, J. Sigelman, “Age-dependent changes in the molecular size of human lens proteins and their relationship to light scatter,” Invest. Ophthalmol. 13, 795–798 (1974). [PubMed]
  11. R. P. Hemenger, “Intraocular light scatter in normal vision loss with age,” Appl. Opt. 23, 1972–1974 (1984). [CrossRef] [PubMed]
  12. M. J. Mayer, B. Ward, R. Klein, J. B. Talcott, R. F. Dougherty, A. Glucs, “Flicker sensitivity and fundus appearance in pre-exudative age-related maculopathy,” Invest. Ophthalmol. Vis. Sci. 35, 1138–1149 (1994). [PubMed]
  13. The nondominant eye was used for testing only if it was determined to be the better eye on preliminary screening for acuity.
  14. C. W. Tyler, “Analysis of visual modulation sensitivity. II. Peripheral retina and the role of photoreceptor dimensions,” J. Opt. Soc. Am. A 2, 393–398 (1985). [CrossRef] [PubMed]
  15. The criteria that we used when deleting data from testing runs were as follows: (1) if the number of trials per test frequency was >30 and (2) if the threshold difference between runs (in decilogs) was ≥5. The use of these criteria resulted in the deletion of 27 out of 1958 (1.38%) threshold estimates, 16 from the first run of testing and 11 from the second run. The use of the first criterion alone resulted in the deletion of 7 out of 1958 (0.36%) threshold estimates for 45 and 50 Hz. There was no differential elimination as a function of either flicker rate or age.
  16. M. Ikeda, “Temporal impulse response,” Vision Res. 26, 1431–1440 (1986). [CrossRef] [PubMed]
  17. M. J. Mayer, S. J. Spiegler, B. Ward, A. Glucs, C. B. Y. Kim, “Foveal flicker sensitivity discriminates ARM-risk from healthy eyes,” Invest. Ophthalmol. Vis. Sci. 33, 133–139 (1992).
  18. D. G. Stork, D. S. Falk, “Temporal impulse responses from flicker sensitivities,” J. Opt. Soc. Am. A 4, 1130–1135 (1987). [CrossRef] [PubMed]
  19. W. H. Swanson, T. Ueno, V. C. Smith, J. Pokorny, “Temporal modulation sensitivity and pulse-detection thresholds for chromatic and luminance perturbations,” J. Opt. Soc. Am. A 4, 1992–2005 (1987). [CrossRef] [PubMed]
  20. Refer to Ref. 19 for details. We used parameters that derived the impulse-response function in 10-ms steps. Sensitivity at 0.5 Hz was set to 10%, and the CSF was fitted with a linear interpolation to the measured 2.5-Hz sensitivity. At the high-frequency end, 12 points from 50.1 to 51.2 Hz were extrapolated from the measured sensitivities at 45 and 50 Hz. A simplex algorithm fitted the rest of the curve.
  21. D. H. Kelly, R. E. Savoie, “A study of sine-wave contrast sensitivity by two psychophysical methods,” Percept. Psychophys. 14, 313–318 (1973). [CrossRef]
  22. J. A. Swets, W. P. Tanner, T. G. Birdsall, “Decision processes in perception,” Psychol. Rev. 68, 301–340 (1961). [CrossRef] [PubMed]
  23. C. W. Tyler, “Analysis of normal flicker sensitivity and its variability in the visuogram test,” Invest. Ophthalmol. Vis. Sci. 32, 2552–2560 (1991). [PubMed]
  24. H. R. Blackwell, “Neural theories of simple visual discriminations,” J. Opt. Soc. Am. 53, 129–160 (1963). [CrossRef] [PubMed]
  25. C. B. Y. Kim, M. J. Mayer, S. Spiegler, “Sensitivity and temporal losses in older observers for foveal flicker detection,” Invest. Ophthalmol. Vis. Sci. Suppl. 30, 313 (1989).
  26. C. W. Tyler, “Specific deficits of flicker sensitivity in glaucoma and ocular hypertension,” Invest. Ophthalmol. Vis. Sci. 20, 204–212 (1981). [PubMed]
  27. We used parameters that derived the digital impulse-response function in 10-ms steps. However, we reasoned that there may be substantial distortion of the peak-time parameters with such coarse sampling, especially for the first and second lobes. To account for the coarse sampling, we redetermined peak-time parameters for the first and second lobes with an algorithm that calculated the intersection point of the straight lines delineating the rising and falling segments of each of the lobes. (We assumed that the lobes of the impulse-response function are symmetric about the peak-time values.) The abscissa value at which the lines intersected was accepted as the recalculated peak-time parameter.
  28. W. Wesemann, “Incoherent image formation in the presence of scattering eye media,” J. Opt. Soc. Am. A 4, 1439–1447 (1987). [CrossRef] [PubMed]
  29. M. J. Mayer, S. J. Spiegler, B. Ward, A. Glucs, C. B. Y. Kim, “Mid-frequency loss of foveal flicker sensitivity in early stages of age-related maculopathy,” Invest. Ophthalmol. Vis. Sci. 33, 126–132 (1992).
  30. M. J. Mayer, S. J. Spiegler, B. Ward, A. Glucs, C. B. Y. Kim, “Preliminary evaluation of flicker sensitivity as a predictive test for exudative age-related maculopathy,” Invest. Ophthalmol. Vis. Sci. 33, 140–145 (1992).
  31. C. W. Tyler, W. Ernst, L. Lyness, “Photopic flicker sensitivity losses in simplex and multiplex retinitis pigmentosa,” Invest. Ophthalmol. Vis. Sci. 25, 1035–1042 (1984). [PubMed]
  32. C. W. Tyler, S. Ryu, R. Stamper, “The relation between visual sensitivity and intraocular pressure in normal eyes,” Invest. Ophthalmol. Vis. Sci. 25, 103–105 (1984). [PubMed]
  33. M. B. Mandler, W. Makous, “A three channel model of temporal frequency perception,” Vision Res. 24, 1881–1887 (1984). [CrossRef] [PubMed]
  34. R. F. Hess, R. J. Snowden, “Temporal properties of human visual filters: number, shapes and spatial covariation,” Vision Res. 32, 47–59 (1992). [CrossRef] [PubMed]

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