Abstract

The time course of the initial negative wave of the flash electroretinogram of the dark-adapted cat has been found to be critically dependent on contributions from cells of the inner retina, not only for very low-intensity flashes for which the negative scotopic threshold response is dominant but also when the stimulus is sufficiently intense for the rods themselves to contribute directly to the electroretinogram. However, if the inner-retinal responses are blocked pharmacologically or are suppressed by a steady adapting background, the initial negative wave of the remaining electroretinogram (the a wave) can be explained as the sum of photoreceptor and bipolar-cell components that can be modeled as described by Lamb and Pugh [ J. Physiol. (London) 449, 717 ( 1992)] and Robson and Frishman [ Vis. Neurosci. 12, 837 ( 1995)], respectively.

© 1996 Optical Society of America

Effects of background light on the human dark-adapted electroretinogram and psychophysical threshold

L. J. Frishman, M. G. Reddy, and J. G. Robson
J. Opt. Soc. Am. A 13(3) 601-612 (1996)

b wave of the scotopic (rod) electroretinogram as a measure of the activity of human on-bipolar cells

Donald C. Hood and David G. Birch
J. Opt. Soc. Am. A 13(3) 623-633 (1996)

Inner retinal contributions to the primate photopic fast flicker electroretinogram

Ronald A. Bush and Paul A. Sieving
J. Opt. Soc. Am. A 13(3) 557-565 (1996)

Rod photoreceptor transduction is affected in central retinal vein occlusion associated with iris neovascularization

Mary A. Johnson and Donald C. Hood
J. Opt. Soc. Am. A 13(3) 572-576 (1996)

Incremental and decremental L- and M-cone-driven ERG responses: I. Square-wave pulse stimulation

Declan McKeefry, Jan Kremers, Deepika Kommanapalli, Naveen K. Challa, Ian J. Murray, John Maguire, and Neil R. A. Parry
J. Opt. Soc. Am. A 31(4) A159-A169 (2014)