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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 16, Iss. 3 — Mar. 1, 1999
  • pp: 621–632

Signal-to-noise optimization of medical imaging systems

Ian A. Cunningham and Rodney Shaw  »View Author Affiliations


JOSA A, Vol. 16, Issue 3, pp. 621-632 (1999)
http://dx.doi.org/10.1364/JOSAA.16.000621


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Abstract

Over recent decades a quiet revolution has taken place in the application of modern imaging theory to many fields of applied imaging. Nowhere has this movement been more dramatic than within the field of diagnostic medical x-ray imaging, to the extent that there is now a growing consensus around a universal imaging language for the description and comparison of the increasingly diverse range of technologies. This common language, which owes much to the basic quantum-limited approach pioneered by Rose and his contemporaries, embodies the fundamentally statistical nature of image signals and enables scientists and engineers to simultaneously develop new system designs optimized for the detection of small signals while constraining patient x-ray exposures to tolerable levels. We attempt to provide a summary of some of the more salient features of progress being made in the understanding of the signal-to-noise limitations of medical imaging systems and to place this progress within a historical context. Emphasis is placed on medical diagnostics based on x-ray imaging techniques.

© 1999 Optical Society of America

OCIS Codes
(110.4280) Imaging systems : Noise in imaging systems
(170.7440) Medical optics and biotechnology : X-ray imaging

History
Original Manuscript: June 11, 1998
Revised Manuscript: November 9, 1998
Manuscript Accepted: July 29, 1998
Published: March 1, 1999

Citation
Ian A. Cunningham and Rodney Shaw, "Signal-to-noise optimization of medical imaging systems," J. Opt. Soc. Am. A 16, 621-632 (1999)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-16-3-621


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References

  1. A. Rose, “Sensitivity performance of the human eye on an absolute scale,” J. Opt. Soc. Am. 38, 196–208 (1948). [CrossRef] [PubMed]
  2. A. Rose, “Television pickup tubes and the problem of vision,” in Advances in Electronics and Electron Physics, L. Marton, ed. (Academic, New York, 1948), pp. 131–166.
  3. A. Rose, “Quantum and noise limitations of the visual process,” J. Opt. Soc. Am. 43, 715–716 (1953). [CrossRef] [PubMed]
  4. A. Rose, “A unified approach to the performance of photographic film, television pick-up tubes, and the human eye,” J. Soc. Motion Pict. Telev. Eng. 47, 273–294 (1946).
  5. A. Rose, Vision: Human and Electronic (Plenum, New York, 1974).
  6. American National Standards Institute, “Methods for the sensitometry of medical x-ray screen–film processing systems,” (American National Standards Institute, New York, 1982).
  7. R. Shaw, “The equivalent quantum efficiency of the photographic process,” J. Photogr. Sci. 11, 199–204 (1963).
  8. M. Rabbani, R. Shaw, R. L. Van Metter, “Detective quantum efficiency of imaging systems with amplifying and scattering mechanisms,” J. Opt. Soc. Am. A 4, 895–901 (1987). [CrossRef] [PubMed]
  9. P. B. Fellgett, “On the ultimate sensitivity and practical performance of radiation detectors,” J. Opt. Soc. Am. 39, 970–976 (1949). [CrossRef] [PubMed]
  10. H. J. Zwieg, “Performance criteria for photo-detectors—concepts in evolution,” Photograph. Sci. Eng. 8, 305 (1964).
  11. R. C. Jones, “A new classification system for radiation detectors,” J. Opt. Soc. Am. 39, 327–343 (1949). [CrossRef] [PubMed]
  12. A. E. Burgess, “The Rose model, revisited,” J. Opt. Soc. Am. A 16, 633–646 (1999). [CrossRef]
  13. K. Rossmann, “Measurement of the modulation transfer function of radiographic systems containing fluorescent screens,” Phys. Med. Biol. 9, 551–557 (1964). [CrossRef]
  14. K. Doi, “Optical transfer functions of the focal spot of x-ray tubes,” Am. J. Roentgenol. 94, 712–718 (1965).
  15. G. Lubberts, K. Rossmann, “Modulation transfer function associated with geometrical unsharpness in medical radiography,” Phys. Med. Biol. 12, 65–77 (1967). [CrossRef] [PubMed]
  16. K. Rossman, G. Sanderson, “Validity of the modulation transfer function of radiographic screen–film systems measured by the slit method,” Phys. Med. Biol. 13, 259–268 (1968). [CrossRef]
  17. K. Rossmann, “The spatial frequency spectrum: a means for studying the quality of radiographic imaging systems,” Radiology 90, 1–13 (1968). [PubMed]
  18. K. Rossmann, “Point spread-function, line spread-function, and modulation transfer function,” Radiology 93, 257–272 (1969). [PubMed]
  19. “Modulation transfer function of screen–film systems,” (International Commission on Radiation Units and Measurements, Bethesda, Md., 1986).
  20. A. E. Burgess, “Focal spots: I. MTF separability,” Invest. Radiol. 12, 36–43 (1977). [CrossRef] [PubMed]
  21. A. E. Burgess, “Focal spots: II. Models,” Invest. Radiol. 12, 44–53 (1977). [CrossRef] [PubMed]
  22. C. E. Metz, K. Doi, “Transfer function analysis of radiographic imaging systems,” Phys. Med. Biol. 24, 1079–1106 (1979). [CrossRef] [PubMed]
  23. J. D. Gaskill, Linear Systems, Fourier Transforms, and Optics (Wiley, New York, 1978).
  24. J. C. Dainty, R. Shaw, Image Science (Academic, New York, 1974).
  25. H. H. Barrett, W. Swindell, Radiological Imaging—The Theory of Image Formation, Detection, and Processing (Academic, New York, 1981).
  26. M. C. Steckner, D. J. Drost, F. S. Prato, “Computing the modulation transfer function of a magnetic resonance imager,” Med. Phys. 21, 483–498 (1994). [CrossRef] [PubMed]
  27. R. F. Wagner, K. E. Weaver, “Noise measurements on rare-earth intensifying screen systems,” in Medical X-Ray Photo-Optical Systems Evaluation, R. F. Wagner, K. E. Weaver, D. G. Goodenough, eds., Proc. SPIE56, 198–207 (1974). [CrossRef]
  28. O. H. Schade, “Evaluation of noisy images,” in Medical X-Ray Photo-Optical Systems Evaluation, R. F. Wagner, K. E. Weaver, D. G. Goodenough, eds., Proc. SPIE56, 107–114 (1974). [CrossRef]
  29. A. Papoulis, Probability, Random Variables, and Stochastic Processes, 3rd ed. (McGraw-Hill, New York, 1991).
  30. I. A. Cunningham, “Analyzing system performance,” in The Expanding Role of Medical Physics in Diagnostic Imaging, G. D. Frey, P. Sprawls, eds. (Advanced Medical Publishing for American Association of Physicists in Medicine, Madison, Wis.1997), pp. 231–263.
  31. “Medical imaging—the assessment of image quality,” (International Commission of Radiation Units and Measurements, Bethesda, Md., 1995).
  32. C. E. Metz, R. F. Wagner, K. Doi, D. G. Brown, R. M. Nishikawa, K. J. Myers, “Toward consensus on quantitative assessment of medical imaging systems,” Med. Phys. 22, 1057–1061 (1995). [CrossRef] [PubMed]
  33. J. T. Dobbins, D. L. Ergun, L. Rutz, D. A. Hinshaw, H. Blume, D. C. Clark, “DQE(f) of four generations of computed radiography acquisition devices,” Med. Phys. 22, 1581–1593 (1995). [CrossRef] [PubMed]
  34. R. Shaw, “Some fundamental properties of xeroradiographic images,” in Application of Optical Instrumentation in Medicine IV, J. E. Gray, W. R. Hendee, eds., Proc. SPIE70, 359–363 (1975). [CrossRef]
  35. R. F. Wagner, E. P. Muntz, “Detective quantum efficiency (DQE) analysis of electrostatic imaging and screen–film imaging in mammography,” in Application of Optical Instrumentation in Medicine VII, J. E. Gray, ed., Proc. SPIE173, 162–165 (1979). [CrossRef]
  36. R. Shaw, R. L. Van Metter, “An analysis of the fundamental limitations of screen–film systems for x-ray detection. I. General theory,” in Application of Optical Instrumentation in Medicine XII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE454, 128–132 (1984). [CrossRef]
  37. R. Shaw, R. L. Van Metter, “An analysis of the fundamental limitations of screen–film systems for x-ray detection. II. Model calculations,” in Application of Optical Instrumentation in Medicine XII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE454, 133–141 (1984). [CrossRef]
  38. P. C. Bunch, R. Shaw, R. L. Van Metter, “Signal-to-noise measurements for a screen–film system,” in Application of Optical Instrumentation in Medicine XII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE454, 154–163 (1984). [CrossRef]
  39. R. Shaw, R. L. Van Metter, “The role of screen and film in determining the noise-equivalent number of quanta recorded by a screen–film system,” in Application of Optical Instrumentation in Medicine XIII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE535, 184–194 (1985). [CrossRef]
  40. P. C. Bunch, K. E. Huff, R. Shaw, R. L. Van Metter, “Comparison of theory and experiment for the DQE of a radiographic screen–film system,” in Application of Optical Instrumentation in Medicine XIII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE535, 166–185 (1985). [CrossRef]
  41. R. L. Van Metter, R. Shaw, “The effect of bias exposure on the detective quantum efficiency of radiographic screen–film systems,” in Application of Optical Instrumentation in Medicine XIII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE535, 157–162 (1985). [CrossRef]
  42. P. L. Dillon, J. F. Hamilton, M. Rabbani, R. Shaw, R. L. Van Metter, “Principles governing the transfer of signal modulation and photon noise by amplifying and scattering mechanisms,” in Application of Optical Instrumentation in Medicine XIII, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE535, 130–139 (1985). [CrossRef]
  43. M. Rabbani, R. L. Van Metter, “Analysis of signal and noise propagation for several imaging mechanisms,” J. Opt. Soc. Am. A 6, 1156–1164 (1989). [CrossRef]
  44. H. J. Zwieg, “Detective quantum efficiency of photodetectors with some amplifying mechanism,” J. Opt. Soc. Am. 55, 525–528 (1965). [CrossRef]
  45. H. H. Barrett, R. F. Wagner, K. J. Myers, “Correlated point processes in radiological imaging,” in Medical Imaging 1997: Physics of Medical Imaging, R. L. Van Metter, J. Beutel, eds., Proc. SPIE3032, 110–125 (1997). [CrossRef]
  46. M. Rabbani, R. Shaw, “The influence of grain threshold on quantum mottle in radiographic film–screen systems,” in Medical Imaging, S. J. Dwyer, R. H. Schneider, eds., Proc. SPIE767, 226–235 (1987). [CrossRef]
  47. M. Rabbani, R. Shaw, “The influence of grain threshold on quantum mottle in radiographic screen–film systems. II,” in Medical Imaging II: Part A—Image Formation, Detection, Processing, and Interpretation, R. H. Schneider, S. J. Dwyer, eds., Proc. SPIE914A, 117–127 (1988). [CrossRef]
  48. M. Rabbani, R. L. Van Metter, “Some new applications of multivariate moment-generating functions to screen–film systems,” in Medical Imaging III: Image Formation, S. J. Dwyer, R. Jost, R. H. Schneider, eds., Proc. SPIE1090, 86–94 (1989). [CrossRef]
  49. R. L. Van Metter, M. Rabbani, “Analysis of the effects of depth dependence of x-ray interactions on the NPS of radiographic screens,” in Medical Imaging IV: Image Formation, R. H. Schneider, ed., Proc. SPIE1231, 271–274 (1990). [CrossRef]
  50. H. Mulder, “Signal and noise transfer through imaging systems consisting of a cascade of amplifying and scattering processes,” J. Opt. Soc. Am. A 10, 2038–2045 (1993). [CrossRef]
  51. R. M. Nishikawa, M. J. Yaffe, “Model of the spatial-frequency-dependent detective quantum efficiency of phosphor screens,” Med. Phys. 17, 894–904 (1990). [CrossRef] [PubMed]
  52. M. M. Ter-Pogossian, The Physical Aspects of Diagnostic Radiology (Harper & Row, New York, 1967).
  53. C. A. Mistretta, “X-ray image intensifiers,” in American Association of Physicists in Medicine Monogr. No. 3, The Physics of Medical Imaging: Recording System Measurements and Techniques, A. G. Haus, ed. (American Institute of Physics, New York, 1979), pp. 182–205.
  54. A. Macovski, Medical Imaging Systems (Prentice-Hall, Englewood Cliffs, N.J., 1983).
  55. H. Roehrig, S. Nudelman, T. Y. Fu, “Electro-optical devices for use in photoelectronic-digital radiology,” in American Association of Physicists in Medicine Monogr. No. 11, Electronic Imaging in Medicine, G. D. Fullerton, W. R. Hendee, J. C. Lasher, W. S. Properzio, S. J. Riederer, eds. (American Institute of Physics, New York, 1984), pp. 82–129.
  56. H. Roehrig, T. Y. Fu, “Physical properties of photoelectronic imaging devices and systems,” in American Association of Physicists in Medicine Monogr. No. 12, Recent Developments in Digital Imaging, K. Doi, L. Lanzl, P. J. P. Lin, eds. (American Institute of Physics, New York, 1985), pp. 82–140.
  57. I. A. Cunningham, M. S. Westmore, A. Fenster, “A spatial-frequency-dependent quantum accounting diagram and detective quantum efficiency model of signal and noise propagation in cascaded imaging systems,” Med. Phys. 21, 417–427 (1994). [CrossRef] [PubMed]
  58. I. A. Cunningham, M. S. Westmore, A. Fenster, “Visual impact of the non-zero spatial frequency quantum sink,” in Medical Imaging 1994: Physics of Medical Imaging, R. Shaw, ed., Proc. SPIE2163, 274–283 (1994). [CrossRef]
  59. J. P. Bissonnette, I. A. Cunningham, D. A. Jaffray, A. Fenster, P. Munro, “A quantum accounting and detective quantum efficiency analysis for video-based portal imaging,” Med. Phys. 24, 815–826 (1997). [CrossRef] [PubMed]
  60. J. H. Siewerdsen, L. E. Antonuk, Y. El-Mohri, J. Yorkston, W. Huang, J. M. Boudry, I. A. Cunningham, “Empirical and theoretical investigation of the noise performance of indirect detection, active matrix flat-panel imagers (AMFPIs) for diagnostic radiology,” Med. Phys. 24, 71–89 (1997). [CrossRef] [PubMed]
  61. J. H. Siewerdsen, L. E. Antonuk, Y. El-Mohri, J. Yorkston, W. Huang, I. A. Cunningham, “Signal, noise power spectrum and detective quantum efficiency of indirect-detection flat-panel imagers for diagnostic radiology,” Med. Phys. 25, 614–628 (1998). [CrossRef] [PubMed]
  62. I. A. Cunningham, “Linear-systems modeling of parallel cascaded stochastic processes: the NPS of radiographic screens with reabsorption of characteristic radiation,” in Medical Imaging 1998: Physics of Medical Imaging, J. T. Dobbins, J. M. Boone, eds., Proc. SPIE3336, 220–230 (1998). [CrossRef]
  63. C. E. Metz, C. J. Vyborny, “Wiener spectral effects of spatial correlation between the sites of characteristic x-ray emission and reabsorption in radiographic screen–film systems,” Phys. Med. Biol. 28, 547–564 (1983). [CrossRef] [PubMed]
  64. W. Hillen, W. Eckenbach, P. Quadflieg, T. Zaengel, “Signal-to-noise performance in cesium iodide x-ray fluorescent screens,” in Medical Imaging V: Image Physics, R. H. Schneider, ed. Proc. SPIE1443, 120–131 (1991). [CrossRef]
  65. I. A. Cunningham, “Degradation of the detective quantum efficiency due to a non-unity detector fill factor,” in Medical Imaging 1997: Physics of Medical Imaging, R. L. Van Metter, J. Beutel, eds., Proc. SPIE3032, 22–31 (1997). [CrossRef]
  66. H. H. Barrett, J. L. Denny, R. F. Wagner, K. J. Myers, “Objective assessment of image quality. II. Fisher information, Fourier crosstalk, and figures of merit for task performance,” J. Opt. Soc. Am. A 12, 834–852 (1995). [CrossRef]
  67. H. H. Barrett, J. L. Denny, H. C. Gifford, C. K. Abbey, R. F. Wagner, K. J. Myers, “Generalized NEQ: Fourier analysis where you would least expect to find it,” in Medical Imaging 1996: Physics of Medical Imaging, R. L. Van Metter, J. Beutel, eds., Proc. SPIE2708, 41–52 (1996). [CrossRef]

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