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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 17, Iss. 3 — Mar. 1, 2000
  • pp: 484–490

Analysis of optical coherence tomography systems based on the extended Huygens–Fresnel principle

Lars Thrane, Harold T. Yura, and Peter E. Andersen  »View Author Affiliations


JOSA A, Vol. 17, Issue 3, pp. 484-490 (2000)
http://dx.doi.org/10.1364/JOSAA.17.000484


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Abstract

We have developed a new theoretical description of the optical coherence tomography (OCT) technique for imaging in highly scattering tissue. The description is based on the extended Huygens–Fresnel principle, valid in both the single- and multiple-scattering regimes. The so-called shower curtain effect, which manifests itself in a standard OCT system, is an inherent property of the present theory. We demonstrate that the shower curtain effect leads to a strong increase in the heterodyne signal in a standard OCT system. This is in contrast to previous OCT models, where the shower curtain effect was not taken into account. The theoretical analysis is verified by measurements on samples consisting of aqueous suspensions of microspheres. Finally, we discuss the use of our new theoretical model for optimization of the OCT system.

© 2000 Optical Society of America

OCIS Codes
(170.1650) Medical optics and biotechnology : Coherence imaging
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6930) Medical optics and biotechnology : Tissue
(170.7050) Medical optics and biotechnology : Turbid media
(290.4210) Scattering : Multiple scattering

Citation
Lars Thrane, Harold T. Yura, and Peter E. Andersen, "Analysis of optical coherence tomography systems based on the extended Huygens–Fresnel principle," J. Opt. Soc. Am. A 17, 484-490 (2000)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-17-3-484


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References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181 (1991).
  2. J. M. Schmitt, A. Knüttel, and R. F. Bonner, “Measurement of optical properties of biological tissues by low-coherence reflectometry,” Appl. Opt. 32, 6032–6042 (1993).
  3. J. M. Schmitt, A. Knüttel, A. S. Gandjbakhche, and R. F. Bonner, “Optical characterization of dense tissues using low-coherence interferometry,” in Holography, Interferometry, and Optical Pattern Recognition in Biomedicine III, H. Podbielska, ed., Proc. SPIE 1889, 197–211 (1993).
  4. M. J. Yadlowsky, J. M. Schmitt, and R. F. Bonner, “Multiple scattering in optical coherence microscopy,” Appl. Opt. 34, 5699–5707 (1995).
  5. M. J. Yadlowsky, J. M. Schmitt, and R. F. Bonner, “Contrast and resolution in the optical coherence microscopy of dense biological tissue,” in Advances in Laser and Light Spectroscopy to Diagnose Cancer and other Diseases II, R. R. Alfano, ed., Proc. SPIE 2387, 193–203 (1995).
  6. Y. Pan, R. Birngruber, and R. Engelhardt, “Contrast limits of coherence-gated imaging in scattering media,” Appl. Opt. 36, 2979–2983 (1997).
  7. J. M. Schmitt and A. Knüttel, “Model of optical coherence tomography of heterogeneous tissue,” J. Opt. Soc. Am. A 14, 1231–1242 (1997).
  8. L. Thrane, H. T. Yura, S. G. Hanson, and P. E. Andersen, “Optical coherence tomography of heterogeneous tissue: calculation of the heterodyne signal,” in Conference on Lasers and Electro-Optics (CLEO/Europe ’98), OSA 1998 Technical Digest Series (Optical Society of America, Washington, D.C., 1998), p. 58.
  9. R. F. Lutomirski and H. T. Yura, “Propagation of a finite optical beam in an inhomogeneous medium,” Appl. Opt. 10, 1652–1658 (1971).
  10. H. T. Yura, “Signal-to-noise ratio of heterodyne lidar systems in the presence of atmospheric turbulence,” Opt. Acta 26, 627–644 (1979).
  11. M. J. C. Van Gemert, S. L. Jacques, H. J. C. M. Sterenborg, and W. M. Star, “Skin optics,” IEEE Trans. Biomed. Eng. 36, 1146–1154 (1989).
  12. A. E. Siegman, Lasers (University Science Books, Mill Valley, Calif., 1986), Sec. 16.1.
  13. C. F. Bohren and D. R. Huffman, Absorption and Scattering of Light by Small Particles (Wiley, New York, 1983).
  14. H. T. Yura and S. G. Hanson, “Effects of receiver optics contamination on the performance of laser velocimeter systems,” J. Opt. Soc. Am. A 13, 1891–1902 (1996).
  15. H. T. Yura and S. G. Hanson, “Optical beam wave propagation through complex optical systems,” J. Opt. Soc. Am. A 4, 1931–1948 (1987).
  16. V. I. Tatarskii, The Effects of the Turbulent Atmosphere on Wave Propagation (National Technical Information Service, Springfield, Va., 1971).
  17. Note that the (algebraically simple) results given below are, strictly speaking, valid only for propagation geometries where A=D, as is obtained in the case of interest.
  18. I. Dror, A. Sandrov, and N. S. Kopeika, “Experimental investigation of the influence of the relative position of the scattering layer on image quality: the shower curtain effect,” Appl. Opt. 37, 6495–6499 (1998).
  19. D. A. Boas, K. K. Bizheva, and A. M. Siegel, “Using dynamic low-coherence interferometry to image Brownian motion within highly scattering media,” Opt. Lett. 23, 319–321 (1998).
  20. R. F. Lutomirski, “Atmospheric degradation of electrooptical system performance,” Appl. Opt. 17, 3915–3921 (1978).

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