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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 17, Iss. 3 — Mar. 1, 2000
  • pp: 589–596

Physiology of L- and M-cone inputs to H1 horizontal cells in the primate retina

Dennis M. Dacey, Lisa C. Diller, Jan Verweij, and David R. Williams  »View Author Affiliations


JOSA A, Vol. 17, Issue 3, pp. 589-596 (2000)
http://dx.doi.org/10.1364/JOSAA.17.000589


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Abstract

In the primate retina, H1 horizontal cells form an electrically coupled network and receive convergent input from long- (L-) and middle- (M-) wavelength-sensitive cones. Using an in vitro preparation of the intact retina to record the light-evoked voltage responses of H1 cells, we systematically varied the L- and M-cone stimulus contrast and measured the relative L- and M-cone input strength for 137 cells across 33 retinas from three Old World species (Macaca nemestrina, M. fascicularis, and Papio anubis). We found that the L- and the M-cone inputs were summed by the H1 cell in proportion to the stimulus cone contrast, which yielded a measure of what we term L- and M-cone contrast gain. The proportion of L-cone contrast gain was highly variable, ranging from 25% to 90% [mean ± standard deviation, (60±14)%]. This variability was accounted for by retinal location within an individual, with the temporal retina showing a consistently higher percentage of L-cone gain, and by large overall variation across individuals, with the mean percentage of L-cone gain ranging from 32% to 80%. We hypothesize that the relative L- and M-cone contrast gain is determined simply by the relative number of L and M cones in the H1 cell’s receptive field and that the variability in L- and M-cone contrast gain reflects a corresponding variability in the mosaic of L and M cones.

© 2000 Optical Society of America

OCIS Codes
(330.0330) Vision, color, and visual optics : Vision, color, and visual optics
(330.1720) Vision, color, and visual optics : Color vision
(330.4270) Vision, color, and visual optics : Vision system neurophysiology
(330.5310) Vision, color, and visual optics : Vision - photoreceptors
(330.5380) Vision, color, and visual optics : Physiology

History
Original Manuscript: July 19, 1999
Revised Manuscript: September 16, 1999
Manuscript Accepted: August 17, 1999
Published: March 1, 2000

Citation
Dennis M. Dacey, Lisa C. Diller, Jan Verweij, and David R. Williams, "Physiology of L- and M-cone inputs to H1 horizontal cells in the primate retina," J. Opt. Soc. Am. A 17, 589-596 (2000)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-17-3-589

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