OSA's Digital Library

Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 18, Iss. 4 — Apr. 1, 2001
  • pp: 932–939

Corrections for inhomogeneities in biological tissue caused by blood vessels

Anne Talsma, Britton Chance, and Reindert Graaff  »View Author Affiliations


JOSA A, Vol. 18, Issue 4, pp. 932-939 (2001)
http://dx.doi.org/10.1364/JOSAA.18.000932


View Full Text Article

Enhanced HTML    Acrobat PDF (192 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

In tissue optics, the assumption that blood is homogeneously distributed in tissue can give rise to miscalculations because blood is found only in blood vessels. In our paper randomly oriented blood vessels are treated as particles for which we obtained apparent absorption and scattering coefficients by means of the Monte Carlo method. Apart from this correction for the contribution of blood properties in tissue, a correction for the contribution of the surrounding tissue proved to be needed as well. The results found with our model were compared with available results from the literature.

© 2001 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.5280) Medical optics and biotechnology : Photon migration
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.7050) Medical optics and biotechnology : Turbid media

History
Original Manuscript: March 1, 2000
Revised Manuscript: September 14, 2000
Manuscript Accepted: October 19, 2000
Published: April 1, 2001

Citation
Anne Talsma, Britton Chance, and Reindert Graaff, "Corrections for inhomogeneities in biological tissue caused by blood vessels," J. Opt. Soc. Am. A 18, 932-939 (2001)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-18-4-932


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. J. W. Severinghaus, P. B. Astrup, “History of blood gas analysis. VI. Oximetry,” J. Clin. Monit. 2, 270–288 (1986). [CrossRef] [PubMed]
  2. B. Chance, “Optical method,” Annu. Rev. Biophys. Biophys. Chem. 20, 1–28 (1991). [CrossRef] [PubMed]
  3. J. W. Severinghaus, J. F. Kelleher, “Recent developments in pulse oximetry,” Anesthesiology 76, 1018–1038 (1992). [CrossRef] [PubMed]
  4. F. F. Jöbsis, “Non-invasive infrared monitoring of central and myocardial oxygen sufficiency and circulatory parameters,” Science 198, 1264–1267 (1977). [CrossRef]
  5. D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys. Med. Biol. 33, 1433–1442 (1988). [CrossRef] [PubMed]
  6. D. A. Benaron, C. D. Kurth, J. M. Steven, M. Delivora-Papadopoulos, B. Chance, “Transcranial optical path length in infants by near-infrared phase-shift spectroscopy,” J. Clin. Monit. 11, 109–117 (1995). [CrossRef] [PubMed]
  7. B. Chance, S. Nikoa, J. Kent, K. McCully, M. Fountain, R. Greenfeld, G. Holtom, “Time-resolved spectroscopy of haemoglobin and myoglobin in resting and ischemic muscle,” Anal. Biochem. 174, 698–707 (1988). [CrossRef] [PubMed]
  8. R. Graaff, A. C. M. Dassel, M. H. Koelink, F. F. M. de Mul, J. G. Aarnoudse, W. G. Zijlstra, “Optical properties of human dermis in vitro and in vivo,” Appl. Opt. 32, 435–447 (1993). [CrossRef] [PubMed]
  9. A. Kienle, M. S. Patterson, “Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium,” J. Opt. Soc. Am. A 14, 246–254 (1997). [CrossRef]
  10. E. Okada, M. Firbank, D. T. Delpy, “The effect of overlying tissue on the spatial sensitivity profile of near-infrared spectroscopy,” Phys. Med. Biol. 40, 2093–2108 (1995). [CrossRef] [PubMed]
  11. T. J. Farrell, M. S. Patterson, M. Essenpreis, “Influence of layered tissue architecture on estimates of tissue optical properties obtained from spatially resolved diffuse reflectometry,” Appl. Opt. 37, 1958–1972 (1998). [CrossRef]
  12. H. Liu, B. Chance, A. H. Hielscher, S. L. Jacques, F. K. Tittel, “Influence of blood vessels on the measurement of hemoglobin oxygenation as determined by time-resolved reflectance spectroscopy,” Med. Phys. 22, 1209–1217 (1995). [CrossRef] [PubMed]
  13. W. Verkruysse, G. W. Lucassen, J. F. de Boer, D. J. Smithies, J. S. Nelson, M. J. C. van Gemert, “Modelling light distributions of homogeneous versus discrete absorbers in light irradiated turbid media,” Phys. Med. Biol. 42, 51–65 (1997). [CrossRef] [PubMed]
  14. M. Firbank, E. Okada, D. T. Delpy, “Investigation of the effect of discrete absorbers upon the measurement of blood volume with near-infrared spectroscopy,” Phys. Med. Biol. 42, 465–477 (1997). [CrossRef] [PubMed]
  15. M. J. C. van Gemert, D. J. Smithies, W. Verkruysse, T. E. Milner, J. S. Nelson, “Wavelengths for port wine stain laser treatment: influence of vessel radius and skin anatomy,” Phys. Med. Biol. 42, 41–50 (1997). [CrossRef] [PubMed]
  16. A. Talsma, R. Graaff, F. F. M. de Mul, W. Ament, J. Greve, “A tissue-optical model to determine changes in saturation and blood volume during ischemia,” in Optical Biopsies, R. Cubeddu, S. R. Mordon, K. Svanberg, eds., Proc. SPIE2627, 186–195 (1995). [CrossRef]
  17. R. Graaff, A. Talsma, F. Folkerts, J. van der Zee, W. Ament, “A three wavelength study on arterial occlusion in skin tissue,” Adv. Exp. Med. Biol. 471, 661–670 (1999). [CrossRef]
  18. R. Graaff, A. C. M. Dassel, M. H. Koelink, J. G. Aarnoudse, F. F. M. de Mul, W. G. Zijlstra, J. Greve, “Condensed Monte Carlo simulations applied to reflectance pulse oximetry,” in Photon Migration and Imaging in Random Media and Tissues, B. Chance, R. R. Alfano, eds., Proc. SPIE1888, 201–212 (1993). [CrossRef]
  19. A. C. M. Dassel, R. Graaff, M. Sikkema, A. Meijer, W. G. Zijlstra, J. G. Aarnoudse, “Reflectance pulse oximetry at the forehead improves by pressure on the probe,” J. Clin. Monit. 11, 237–244 (1995). [CrossRef] [PubMed]
  20. R. Graaff, A. C. M. Dassel, W. G. Zijlstra, F. F. M. de Mul, J. G. Aarnoudse, “Phase delays in reflectance pulse oximetry: a Monte Carlo study,” in Optical Imaging Techniques for Biomonitoring, H. J. Foth, R. Marchesini, H. Podbielska, M. Robert-Nicoud, H. Schneckenburger, eds., Proc. SPIE2628, 361–368 (1995). [CrossRef]
  21. H. C. van de Hulst, Light Scattering by Small Particles (Wiley, New York, 1957), Sec. 4.3.
  22. L. G. Henyey, J. L. Greenstein, “Diffuse radiation in the galaxy,” Astrophys. J. 93, 70–83 (1941). [CrossRef]
  23. R. Graaff, M. H. Koelink, F. F. M. de Mul, W. G. Zijlstra, A. C. M. Dassel, J. G. Aarnoudse, “Condensed Monte Carlo simulations for the description of light transport,” Appl. Opt. 32, 426–434 (1993). [CrossRef] [PubMed]
  24. S. R. Arridge, W. R. B. Lionheart, “Nonuniqueness in diffusion-based optical tomography,” Opt. Lett. 23, 882–884 (1998). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 
Fig. 4 Fig. 5
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited