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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 19, Iss. 1 — Jan. 1, 2002
  • pp: 197–207

Imaging of the optic disc and retinal nerve fiber layer: the effects of age, optic disc area, refractive error, and gender

Christopher Bowd, Linda M. Zangwill, Eytan Z. Blumenthal, Cristiana Vasile, Andreas G. Boehm, Parag A. Gokhale, Kourosh Mohammadi, Payam Amini, Timothy M. Sankary, and Robert N. Weinreb  »View Author Affiliations


JOSA A, Vol. 19, Issue 1, pp. 197-207 (2002)
http://dx.doi.org/10.1364/JOSAA.19.000197


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Abstract

We cross-sectionally examined the relationship between age, optic disc area, refraction, and gender and optic disc topography and retinal nerve fiber layer (RNFL) measurements, using optical imaging techniques. One eye from each of 155 Caucasian subjects (age range 23.0–80.8 y) without ocular pathology was included. Measurements were obtained by using the Heidelberg Retina Tomography (HRT), the GDx Nerve Fiber Analyzer, and the Optical Coherence Tomograph (OCT). The effects of age were small (R2<17%) and were limited to specific HRT, GDx, and OCT parameters. Disc area was significantly associated with most HRT parameters and isolated GDx and OCT parameters. Refraction and gender were not significantly associated with any optic disc or RNFL parameters. Although effects of age on the optic disc and RNFL are small, they should be considered in monitoring ocular disease. Optic disc area should be considered when cross-sectionally evaluating disc topography and, to a lesser extent, RNFL thickness.

© 2002 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

Citation
Christopher Bowd, Linda M. Zangwill, Eytan Z. Blumenthal, Cristiana Vasile, Andreas G. Boehm, Parag A. Gokhale, Kourosh Mohammadi, Payam Amini, Timothy M. Sankary, and Robert N. Weinreb, "Imaging of the optic disc and retinal nerve fiber layer: the effects of age, optic disc area, refractive error, and gender," J. Opt. Soc. Am. A 19, 197-207 (2002)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-19-1-197


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