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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Vol. 20, Iss. 2 — Feb. 1, 2003
  • pp: 357–367

Cartilage thickness measurements from optical coherence tomography

Jadwiga Rogowska, Clifford M. Bryant, and Mark E. Brezinski  »View Author Affiliations


JOSA A, Vol. 20, Issue 2, pp. 357-367 (2003)
http://dx.doi.org/10.1364/JOSAA.20.000357


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Abstract

We describe a new semiautomatic image processing method for detecting the cartilage boundaries in optical coherence tomography (OCT). In particular, we focus on rabbit cartilage since this is an important animal model for testing both chondroprotective agents and cartilage repair techniques. The novel boundary-detection system presented here consists of (1) an adaptive filtering technique for image enhancement and speckle reduction, (2) edge detection, and (3) edge linking by graph searching. The procedure requires several steps and can be automated. The quantitative measurements of cartilage thickness on OCT images correlated well with measurements from histology.

© 2003 Optical Society of America

OCIS Codes
(100.0100) Image processing : Image processing
(100.2000) Image processing : Digital image processing
(100.2960) Image processing : Image analysis
(100.2980) Image processing : Image enhancement
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

History
Original Manuscript: June 10, 2002
Manuscript Accepted: August 19, 2002
Published: February 1, 2003

Citation
Jadwiga Rogowska, Clifford M. Bryant, and Mark E. Brezinski, "Cartilage thickness measurements from optical coherence tomography," J. Opt. Soc. Am. A 20, 357-367 (2003)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-20-2-357


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