Characteristics of tissue birefringence provide valuable diagnostic information when optical coherence tomography (OCT) imaging is performed. We mathematically model single-detector polarization-sensitive (PS) OCT (PS-OCT) for imaging an alternating layered phantom with birefringence. The theoretical analysis and the simulated data all reveal complexities associated with PS-OCT imaging. Various tissue parameters affect the retrieved PS-OCT signal and hence the image features. A better understanding of the mechanisms that control PS-OCT imaging would be useful for interpretation of tissue images and ultimately useful to provide more diagnostic information.
© 2005 Optical Society of America
Original Manuscript: June 23, 2004
Revised Manuscript: August 17, 2004
Manuscript Accepted: August 24, 2004
Published: February 1, 2005
Bin Liu, Michelle Harman, and Mark E. Brezinski, "Variables affecting polarization-sensitive optical coherence tomography imaging examined through the modeling of birefringent phantoms," J. Opt. Soc. Am. A 22, 262-271 (2005)