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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Editor: Stephen A. Burns
  • Vol. 23, Iss. 9 — Sep. 1, 2006
  • pp: 2097–2104

Interferometric imaging of the full thickness of the precorneal tear film

P. Ewen King-Smith, Barbara A. Fink, Jason J. Nichols, Kelly K. Nichols, and Richard M. Hill  »View Author Affiliations


JOSA A, Vol. 23, Issue 9, pp. 2097-2104 (2006)
http://dx.doi.org/10.1364/JOSAA.23.002097


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Abstract

A method is described for recording interference images from the full thickness of the precorneal tear film (PCTF). Simultaneous images are recorded by two video cameras. One camera responds to broadband spectral illumination and records interference from the superficial lipid layer of the tear film. The other camera uses narrowband illumination and records interference from both the lipid layer and the full thickness of the PCTF. Thus the full-thickness interference fringes are derived from the difference between, or ratio of, narrowband broadband images. This method has the potential for evaluating the role of both tear film flow and evaporation in tear film thinning and breakup. It therefore may be applied to the analysis of dry eye disease.

© 2006 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(260.3160) Physical optics : Interference
(310.6860) Thin films : Thin films, optical properties

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 21, 2005
Revised Manuscript: February 24, 2006
Manuscript Accepted: March 1, 2006

Virtual Issues
Vol. 1, Iss. 10 Virtual Journal for Biomedical Optics

Citation
P. Ewen King-Smith, Barbara A. Fink, Jason J. Nichols, Kelly K. Nichols, and Richard M. Hill, "Interferometric imaging of the full thickness of the precorneal tear film," J. Opt. Soc. Am. A 23, 2097-2104 (2006)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-23-9-2097


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