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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Editor: Stephen A. Burns
  • Vol. 24, Iss. 5 — May. 1, 2007
  • pp: 1426–1430

Relating retinal nerve fiber thickness to behavioral sensitivity in patients with glaucoma: application of a linear model

Donald C. Hood  »View Author Affiliations


JOSA A, Vol. 24, Issue 5, pp. 1426-1430 (2007)
http://dx.doi.org/10.1364/JOSAA.24.001426


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Abstract

Glaucoma causes damage to the retinal ganglion cells and their axons, and this damage can be detected with both structural and functional tests. The purpose of this study was to better understand the relationship between a structural measure of retinal nerve fiber layer (RNFL) and the most common functional test, behavioral sensitivity with static automated perimetry (SAP). First, a linear model, previously shown to describe the relationship between local visual evoked potentials and SAP sensitivity, was modified to predict the change in RNFL as measured by optical coherence tomography. Second, previous work by others was shown to be consistent with this model.

© 2007 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment
(330.5370) Vision, color, and visual optics : Physiological optics

ToC Category:
Clinical Applications of Retinal Imaging

History
Original Manuscript: July 31, 2006
Revised Manuscript: October 18, 2006
Manuscript Accepted: October 21, 2006
Published: April 11, 2007

Virtual Issues
Vol. 2, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Donald C. Hood, "Relating retinal nerve fiber thickness to behavioral sensitivity in patients with glaucoma: application of a linear model," J. Opt. Soc. Am. A 24, 1426-1430 (2007)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-24-5-1426

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