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Journal of the Optical Society of America A

Journal of the Optical Society of America A

| OPTICS, IMAGE SCIENCE, AND VISION

  • Editor: Franco Gori
  • Vol. 27, Iss. 10 — Oct. 1, 2010
  • pp: 2216–2228

Image formation and tomogram reconstruction in optical coherence microscopy

Martin Villiger and Theo Lasser  »View Author Affiliations


JOSA A, Vol. 27, Issue 10, pp. 2216-2228 (2010)
http://dx.doi.org/10.1364/JOSAA.27.002216


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Abstract

In this work we present a model for image formation in optical coherence microscopy. In the spectral domain detection, each wavenumber has a specific coherent transfer function that samples a different part of the object’s spatial frequency spectrum. The reconstruction of the tomogram is usually accurate only in a short depth of field. Using numerical simulations based on the developed model, we identified two distinct mechanisms that influence the signal of out-of-focus sample information. Besides the lateral blurring induced through defocusing, an additional axial envelope contributing equally to the signal degradation was found.

© 2010 Optical Society of America

OCIS Codes
(110.1650) Imaging systems : Coherence imaging
(110.6880) Imaging systems : Three-dimensional image acquisition
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(180.1655) Microscopy : Coherence tomography
(110.6955) Imaging systems : Tomographic imaging

ToC Category:
Microscopy

History
Original Manuscript: July 12, 2010
Manuscript Accepted: July 29, 2010
Published: September 22, 2010

Virtual Issues
Vol. 5, Iss. 14 Virtual Journal for Biomedical Optics

Citation
Martin Villiger and Theo Lasser, "Image formation and tomogram reconstruction in optical coherence microscopy," J. Opt. Soc. Am. A 27, 2216-2228 (2010)
http://www.opticsinfobase.org/josaa/abstract.cfm?URI=josaa-27-10-2216


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References

  1. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, “Performance of Fourier domain vs. time domain optical coherence tomography,” Opt. Express 11, 889–894 (2003). [CrossRef] [PubMed]
  2. J. A. Izatt, M. R. Hee, G. M. Owen, E. A. Swanson, and J. G. Fujimoto, “Optical coherence microscopy in scattering media,” Opt. Lett. 19, 590–592 (1994). [CrossRef] [PubMed]
  3. S. W. Huang, A. D. Aguirre, R. A. Huber, D. C. Adler, and J. G. Fujimoto, “Swept source optical coherence microscopy using a Fourier domain mode-locked laser,” Opt. Express 15, 6210–6217 (2007). [CrossRef] [PubMed]
  4. M. A. Choma, A. K. Ellerbee, C. H. Yang, T. L. Creazzo, and J. A. Izatt, “Spectral-domain phase microscopy,” Opt. Lett. 30, 1162–1164 (2005). [CrossRef] [PubMed]
  5. C. Joo, T. Akkin, B. Cense, B. H. Park, and J. E. de Boer, “Spectral-domain optical coherence phase microscopy for quantitative phase-contrast imaging,” Opt. Lett. 30, 2131–2133 (2005). [CrossRef] [PubMed]
  6. Y. Yasuno, J. I. Sugisaka, Y. Sando, Y. Nakamura, S. Makita, M. Itoh, and T. Yatagai, “Non-iterative numerical method for laterally superresolving Fourier domain optical coherence tomography,” Opt. Express 14, 1006–1020 (2006). [CrossRef] [PubMed]
  7. L. F. Yu, B. Rao, J. Zhang, J. P. Su, Q. Wang, S. G. Guo, and Z. P. Chen, “Improved lateral resolution in optical coherence tomography by digital focusing using two-dimensional numerical diffraction method,” Opt. Express 15, 7634–7641 (2007). [CrossRef] [PubMed]
  8. T. S. Ralston, D. L. Marks, P. S. Carney, and S. A. Boppart, “Interferometric synthetic aperture microscopy,” Nat. Phys. 3, 129–134 (2007). [CrossRef]
  9. Z. H. Ding, H. W. Ren, Y. H. Zhao, J. S. Nelson, and Z. P. Chen, “High-resolution optical coherence tomography over a large depth range with an axicon lens,” Opt. Lett. 27, 243–245 (2002). [CrossRef]
  10. K. S. Lee and L. P. Rolland, “Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range,” Opt. Lett. 33, 1696–1698 (2008). [CrossRef] [PubMed]
  11. L. B. Liu, F. Diaz, L. Wang, B. Loiseaux, J. P. Huignard, C. J. R. Sheppard, and N. G. Chen, “Superresolution along extended depth of focus with binary-phase filters for the Gaussian beam,” J. Opt. Soc. Am. A 25, 2095–2101 (2008). [CrossRef]
  12. K. M. Tan, M. Mazilu, T. H. Chow, W. M. Lee, K. Taguchi, B. K. Ng, W. Sibbett, C. S. Herrington, C. T. A. Brown, and K. Dholakia, “In-fiber common-path optical coherence tomography using a conical-tip fiber,” Opt. Express 17, 2375–2384 (2009). [CrossRef] [PubMed]
  13. R. A. Leitgeb, M. Villiger, A. H. Bachmann, L. Steinmann, and T. Lasser, “Extended focus depth for Fourier domain optical coherence microscopy,” Opt. Lett. 31, 2450–2452 (2006). [CrossRef] [PubMed]
  14. T. S. Ralston, D. L. Marks, P. S. Carney, and S. A. Boppart, “Inverse scattering for optical coherence tomography,” J. Opt. Soc. Am. A 23, 1027–1037 (2006). [CrossRef]
  15. T. S. Ralston, D. L. Marks, S. A. Boppart, and P. S. Carney, “Inverse scattering for high-resolution interferometric microscopy,” Opt. Lett. 31, 3585–3587 (2006). [CrossRef] [PubMed]
  16. P. H. Tomlins and R. K. Wang, “Theory, developments and applications of optical coherence tomography,” J. Phys. D: Appl. Phys. 38, 2519–2535 (2005). [CrossRef]
  17. A. F. Fercher, W. Drexler, C. K. Hitzenberger, and T. Lasser, “Optical coherence tomography—principles and applications,” Rep. Prog. Phys. 66, 239–303 (2003). [CrossRef]
  18. C. J. R. Sheppard, M. Roy, and M. D. Sharma, “Image formation in low-coherence and confocal interference microscopes,” Appl. Opt. 43, 1493–1502 (2004). [CrossRef] [PubMed]
  19. J. M. Coupland and J. Lobera, “Holography, tomography and 3d microscopy as linear filtering operations,” Meas. Sci. Technol. 19, 074012 (2008). [CrossRef]
  20. C. W. McCutchen, “Generalized aperture and the three-dimensional diffraction image,” J. Opt. Soc. Am. 54, 240–244 (1964). [CrossRef]
  21. C. J. R. Sheppard, M. Gu, Y. Kawata, and S. Kawata, “Three-dimensional transfer functions for high-aperture systems,” J. Opt. Soc. Am. A 11, 593–598 (1994). [CrossRef]
  22. M. Gu, Advanced Optical Imaging Theory, Vol. 75 of Springer Series in Optical Sciences (Springer, 2000).
  23. R. A. Leitgeb, R. Michaely, T. Lasser, and S. C. Sekhar, “Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning,” Opt. Lett. 32, 3453–3455 (2007). [CrossRef] [PubMed]
  24. A. H. Bachmann, R. A. Leitgeb, and T. Lasser, “Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution,” Opt. Express 14, 1487–1496 (2006). [CrossRef] [PubMed]
  25. B. Baumann, M. Pircher, E. Gotzinger, and C. K. Hitzenberger, “Full range complex spectral domain optical coherence tomography without additional phase shifters,” Opt. Express 15, 13375–13387 (2007). [CrossRef] [PubMed]
  26. S. Yun, G. Tearney, J. de Boer, and B. Bouma, “Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting,” Opt. Express 12, 4822–4828 (2004). [CrossRef] [PubMed]
  27. B. Liu and M. E. Brezinski, “Theoretical and practical considerations on detection performance of time domain, Fourier domain, and swept source optical coherence tomography,” J. Biomed. Opt. 12, 044007 (2007). [CrossRef] [PubMed]
  28. J. H. McLeod, “The axicon—a new type of optical element,” J. Opt. Soc. Am. 44, 592–597 (1954). [CrossRef]
  29. M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of langerhans with extended-focus optical coherence microscopy,” Diabetologia 52, 1599–1607 (2009). [CrossRef] [PubMed]

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