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Journal of the Optical Society of America A

Journal of the Optical Society of America A


  • Editor: Franco Gori
  • Vol. 28, Iss. 4 — Apr. 1, 2011
  • pp: 517–522

Speckle properties of the logarithmically transformed signal in optical coherence tomography

Peng Lee, Wanrong Gao, and Xianling Zhang  »View Author Affiliations

JOSA A, Vol. 28, Issue 4, pp. 517-522 (2011)

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We discuss the statistical properties of speckle of the logarithmically transformed signal in optical coherence tomography (OCT) both theoretically and experimentally. OCT signals of Intralipid solution with different volume particle concentrations ρ (correspondingly, scattering coefficient μ s ranges from 1.25 to 25.11 mm 1 ) were measured and analyzed under two different focusing conditions [numerical apertures (NAs) of the objective lens of 0.13 and 0.25]. We found that the effect of the speckle noise can be suppressed by displaying OCT images in the logarithmic scale and by using the objective lens with a higher NA. We also found that the speckle properties are correlated with the scattering properties of the sample, which may be used to characterize the scattering properties of biological tissue. The simulated OCT image and the in vitro OCT image of a rat liver are used as examples to demonstrate the feasibility of the method.

© 2011 Optical Society of America

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(290.5820) Scattering : Scattering measurements

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: September 17, 2010
Revised Manuscript: January 13, 2011
Manuscript Accepted: January 17, 2011
Published: March 7, 2011

Virtual Issues
Vol. 6, Iss. 5 Virtual Journal for Biomedical Optics

Peng Lee, Wanrong Gao, and Xianling Zhang, "Speckle properties of the logarithmically transformed signal in optical coherence tomography," J. Opt. Soc. Am. A 28, 517-522 (2011)

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