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Journal of the Optical Society of America A

Journal of the Optical Society of America A


  • Editor: Franco Gori
  • Vol. 29, Iss. 2 — Feb. 1, 2012
  • pp: A69–A73

Chromatic visual evoked potential responses in preschool children

Manca Tekavčič Pompe, Branka Stirn Kranjc, and Jelka Brecelj  »View Author Affiliations

JOSA A, Vol. 29, Issue 2, pp. A69-A73 (2012)

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The purpose of the study was to analyze chromatic visual evoked potential (VEP) responses to isoluminant red–green (R–G) and blue–yellow (B–Y) stimuli in 30 preschool children (1.5–6  years). The predominant part of the response consisted of a positive (P) wave, which showed age-related latency changes (linear decrease). P wave latency was shorter when using 21° compared to 7° R–G (p=0.004) and B–Y (p=0.044) stimulus and also when using 21° R–G compared to 21° B–Y stimulus (P=0.000). P wave amplitude did not show age-related changes. However, a lower amplitude was recorded when using 7° R–G stimulus (p=0.0013) and also when using B–Y compared to R–G stimulus. We may conclude that chromatic VEP to R–G and B–Y stimuli is reliably recorded in preschool children and that P wave to R–G stimulation shows a higher amplitude and shorter latency than to B–Y stimulus.

© 2012 Optical Society of America

OCIS Codes
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.5380) Medical optics and biotechnology : Physiology
(330.0330) Vision, color, and visual optics : Vision, color, and visual optics
(010.1690) Atmospheric and oceanic optics : Color

ToC Category:
Retinal and cortical color processing

Original Manuscript: August 26, 2011
Revised Manuscript: October 26, 2011
Manuscript Accepted: October 30, 2011
Published: January 13, 2012

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Vol. 7, Iss. 4 Virtual Journal for Biomedical Optics

Manca Tekavčič Pompe, Branka Stirn Kranjc, and Jelka Brecelj, "Chromatic visual evoked potential responses in preschool children," J. Opt. Soc. Am. A 29, A69-A73 (2012)

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  1. J. Murray, N. R. A. Parry, D. Carden, and J. J. Kulikowski, “Human visual evoked potentials to chromatic and achromatic gratings,” Clin. Vis. Sci. 1, 231–244 (1986).
  2. T. A. Berninger, G. B. Arden, C. R. Hogg, and T. Frumkes, “Separable evoked retinal and cortical potentials from each major visual pathway: preliminary results,” Br. J. Ophthalmol. 73, 502–511 (1989). [CrossRef]
  3. J. Rabin, E. Switkes, M. Crognale, M. E. Schneck, and A. J. Adams, “Visual evoked potentials in three-dimensional colour space: correlates of spatio-chromatic processing,” Vis. Res. 34, 2657–2671 (1994). [CrossRef]
  4. J. J. Kulikowski, A. G. Robson, and D. J. McKeefry, “Specificity and selectivity of chromatic visual evoked potentials,” Vis. Res. 36, 3397–3401 (1996). [CrossRef]
  5. D. J. McKeefry, I. J. Murray, and J. J. Kulikowski, “Pattern ERG from isoluminant gratings; poor selectivity compared with VEPS,” Ophthalmic Physiol. Opt. 17, 499–508 (1997). [CrossRef]
  6. C. M. Suttle and G. F. A. Harding, “Morphology of transient VEPs to luminance and chromatic pattern onset and offset,” Vis. Res. 39, 1577–1584 (1999). [CrossRef]
  7. V. Porciatti and F. Sartucci, “Normative data for onset VEPs to red–green and blue–yellow chromatic contrast,” Clin. Neurophysiol. 110, 722–781 (1999).
  8. M. C. Morrone, A. Fiorentini, and D. C. Burr, “Development of the temporal properties of visual evoked potentials to luminance and colour contrasts in infants,” Vis. Res. 36, 3141–3155(1996). [CrossRef]
  9. M. A. Crognale, J. P. Kelly, A. H. Weiss, and D. Y. Teller, “Development of the spatio-chromatic visual evoked potential (VEP): a longitudinal study,” Vis. Res. 38, 3283–3292(1998). [CrossRef]
  10. G. E. Gordon and D. McCulloch, “A VEP investigation of parallel visual pathway development in primary school age children,” Doc. Ophthalmol. 99, 1–10 (1999). [CrossRef]
  11. M. Madrid and M. A. Crognale, “Long-term maturation of visual pathways,” Vis. Neurosci. 17, 831–837 (2000). [CrossRef]
  12. M. A. Crognale, “Development, maturation and aging of chromatic visual pathways: VEP results,” J. Vis. 2, 438–450(2002). [CrossRef]
  13. Y. T. Elia, D. Daneman, J. Rovet, M. Abdolell, W. C. Lam, C. Till, V. Erraguntla, S. Rubab, N. Lodba, and C. A. Westall, “Color visual evoked potentials in children with type 1 diabetes: relationship to metabolic control,” Invest. Ophthalmol. Visual Sci. 46, 4107–4113 (2005). [CrossRef]
  14. M. T. Pompe, B. Stirn Kranjc, and J. Brecelj, “Visual evoked potentials to red–green stimulation in schoolchildren,” Vis. Neurosci. 23, 447–451 (2006).
  15. M. Y. Boon, C. M. Suttle, and S. J. Dain, “Transient VEP and psychophysical chromatic contrast thresholds in children and adults,” Vis. Res. 47, 2124–2133 (2007). [CrossRef]
  16. M. Y. Boon, C. M. Suttle, B. I. Henry, and S. J. Dain, “Dynamics of chromatic visual system processing differ in complexity between children and adults,” J. Vis. 22, 1–17 (2009).
  17. M. Tekavčič Pompe, B. Stirn Kranjc, and J. Brecelj, “Chromatic VEP in children with congenital colour vision deficiency,” Ophthalmic Physiol. Opt. 30, 693–698 (2010). [CrossRef]
  18. D. Carden, J. J. Kulikowski, I. J. Murray, and N. R. A. Parry, “Human occipital potentials evoked by the onset of equiluminant chromatic gratings,” J. Physiol. 369, 44 (1985).
  19. F. H. Previc, “Visual evoked potentials to luminance and chromatic contrast in rhesus monkeys,” Vis. Res. 26, 1897–1907 (1986). [CrossRef]
  20. N. R. A. Parry and I. J. Murray, “Electrophysiological investigation of adult and infant colour vision deficiencies,” in John Dalton’s Colour Vision Legacy: Selected Proceedings of the International Conference, C. Dickinson, I. J. Murray, and D. Carden, eds. (Taylor & Francis, 1997), pp. 349–357.
  21. F. Sharbrough, G.-E. Chatrian, R. P. Lesser, H. Lüders, M. Nuwer, and T. W. Picton, “American Encephalographic Society guidelines for standard electrode placement nomenclature,” J. Clin. Neurophysiol. 8, 200–202 (1991). [CrossRef]
  22. J. J. Kulikowski, I. J. Murray, and M. H. A. Russell, “Effects of stimulus size on chromatic and achromatic VEPs,” in Colour Vision Deficiencies XB. Drum, J. D. Moreland, and A. Serra, eds. (Kluwer, 1991), pp. 51–66.
  23. G. Robson, G. E. Holder, J. D. Moreland, and J. J. Kulikowski, “Chromatic VEP assessment of human macular pigment: comparison with minimum motion and minimum flicker profiles,” Vis. Neurosci. 23, 275–283 (2006). [CrossRef]
  24. R. A. Bone, J. T. Landrum, L. Fernandez, and S. L. Tarsis, “Analysis of the macular pigment by HPLC: retinal distribution and age study,” Invest. Ophthalmol. Vis. Sci. 29, 843–849 (1988).

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