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Journal of the Optical Society of America A

Journal of the Optical Society of America A


  • Editor: Franco Gori
  • Vol. 30, Iss. 12 — Dec. 1, 2013
  • pp: 2466–2472

Elastomeric 2D grating and hemispherical optofluidic chamber for multifunctional fluidic sensing

Zhida Xu, Xinhao Wang, Kevin Han, Shuo Li, and G. Logan Liu  »View Author Affiliations

JOSA A, Vol. 30, Issue 12, pp. 2466-2472 (2013)

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We present an optofluidic sensor based on an elastomeric two-dimensional (2D) grating integrated inside a hemispherical fluid chamber. A laser beam is diffracted before (reflection) and after (transmission) going through the grating and liquid in the dome chamber. The sensing mechanism is investigated and simulated with a finite-difference time-domain-based electromagnetic method. For the experiment, by analyzing the size, power, and shape of the 2D diffraction patterns, we can retrieve multiple parameters of the liquid, including the refractive index, pressure, and opacity with high sensitivity. We demonstrate that the glucose concentration can be monitored when mixed in a different concentrated phosphate-buffered saline solution. The free-solution binding of bovine serum albumin (BSA) and anti-BSA IgG is detected with this optical sensor. This low-cost, multifunctional, and reliable optofluidic sensor has the potential to be used as a monitor of biofluid, such as blood in hemodialysis.

© 2013 Optical Society of America

OCIS Codes
(050.1950) Diffraction and gratings : Diffraction gratings
(280.4788) Remote sensing and sensors : Optical sensing and sensors

ToC Category:
Remote Sensing and Sensors

Original Manuscript: July 29, 2013
Revised Manuscript: October 11, 2013
Manuscript Accepted: October 17, 2013
Published: November 8, 2013

Virtual Issues
Vol. 9, Iss. 2 Virtual Journal for Biomedical Optics

Zhida Xu, Xinhao Wang, Kevin Han, Shuo Li, and G. Logan Liu, "Elastomeric 2D grating and hemispherical optofluidic chamber for multifunctional fluidic sensing," J. Opt. Soc. Am. A 30, 2466-2472 (2013)

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