OSA's Digital Library

Journal of the Optical Society of America B

Journal of the Optical Society of America B

| OPTICAL PHYSICS

  • Editor: Henry M. Van Driel
  • Vol. 24, Iss. 11 — Nov. 1, 2007
  • pp: 2779–2783

Emulated transmission in confocal Raman microscopy

Pavel V. Zinin, Anupam Misra, Lori Kamemoto, Qigui Yu, and Shiv K. Sharma  »View Author Affiliations


JOSA B, Vol. 24, Issue 11, pp. 2779-2783 (2007)
http://dx.doi.org/10.1364/JOSAB.24.002779


View Full Text Article

Enhanced HTML    Acrobat PDF (446 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We propose to use a mirror to simulate transmission configuration in a reflection confocal optical and Raman microscopy. Such a configuration allows an increased contrast of optical images of cells and increases the efficiency of Raman signal detection from cells by a factor of two.

© 2007 Optical Society of America

OCIS Codes
(140.0140) Lasers and laser optics : Lasers and laser optics
(140.3550) Lasers and laser optics : Lasers, Raman
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1530) Medical optics and biotechnology : Cell analysis

ToC Category:
Lasers and Laser Optics

History
Original Manuscript: July 25, 2007
Revised Manuscript: September 3, 2007
Manuscript Accepted: September 5, 2007
Published: October 11, 2007

Virtual Issues
Vol. 2, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Pavel V. Zinin, Anupam Misra, Lori Kamemoto, Qigui Yu, and Shiv K. Sharma, "Emulated transmission in confocal Raman microscopy," J. Opt. Soc. Am. B 24, 2779-2783 (2007)
http://www.opticsinfobase.org/josab/abstract.cfm?URI=josab-24-11-2779


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. G. J. Puppels, F. F. M. Demul, C. Otto, J. Greve, M. Robertnicoud, D. J. Arndtjovin, and T. M. Jovin, "Studying single living cells and chromosomes by confocal Raman microscopy," Nature (London) 347, 301-303 (1990). [CrossRef]
  2. Y. S. Huang, T. Karashima, M. Yamamoto, T. Ogura, and H. Hamaguchi, "Raman spectroscopic signature of life in a living yeast cell," J. Raman Spectrosc. 35, 525-526 (2004). [CrossRef]
  3. Y. Naito, A. Toh-e, and H. O. Hamaguchi, "In vivo time-resolved Raman imaging of a spontaneous death process of a single budding yeast cell," J. Raman Spectrosc. 36, 837-839 (2005). [CrossRef]
  4. C. G. Xie, Y. Q. Li, W. Tang, and R. J. Newton, "Study of dynamical process of heat denaturation in optically trapped single microorganisms by near-infrared Raman spectroscopy," J. Appl. Phys. 94, 6138-6142 (2003). [CrossRef]
  5. C. J. R. Sheppard and C. J. Cogswell, "Reflection and transmission confocal microscopy," in Optics in Medicine, Biology and Environmental Research, G.von Bally and S.Khanna, eds. (Elsevier, 1993), pp. 310-315.
  6. W. Weise, P. Zinin, T. Wilson, A. Briggs, and S. Boseck, "Imaging of spheres with the confocal scanning optical microscope," Opt. Lett. 21, 1800-1802 (1996). [CrossRef] [PubMed]
  7. J. F. Aguilar, M. Lera, and C. J. R. Sheppard, "Imaging of spheres and surface profiling by confocal microscopy," Appl. Opt. 39, 4621-4628 (2000). [CrossRef]
  8. W. Weise, P. Zinin, A. Briggs, T. Wilson, and S. Boseck, "Examination of the two-dimensional pupil function in coherent scanning microscopes using spherical particles," J. Acoust. Soc. Am. 104, 181-191 (1998). [CrossRef] [PubMed]
  9. J. D. Jackson, Classical Electrodynamics (Wiley, 1995).
  10. M.Abramovitz and I.Stegun, eds., Handbook of Mathematical Functions (Dover, 1970).
  11. K. Kvien, "Angular spectrum representation of fields diffracted by spherical objects: physical properties and implementations of image field models," J. Opt. Soc. Am. A 15, 636-651 (1998). [CrossRef]
  12. C. J. R. Sheppard and T. Wilson, "Effects of high angles of convergence on V(Z) in the scanning acoustic microscope," Appl. Phys. Lett. 38, 858-859 (1981). [CrossRef]
  13. P. Zinin, W. Weise, O. Lobkis, and S. Boseck, "The theory of three-dimensional imaging of strong scatterers in scanning acoustic microscopy," Wave Motion 25, 213-236 (1997). [CrossRef]
  14. M. Hammer, D. Schweitzer, B. Michel, E. Thamm, and A. Kolb, "Single scattering by red blood cells," Appl. Opt. 37, 7410-7418 (1998). [CrossRef]
  15. P. Zinin, W. Weise, T. Zhai, G. A. D. Briggs, and S. Boseck, "Determination of the defocused transfer function of a confocal reflection microscope by imaging of a sphere," Optik (Jena) 107, 45-48 (1997).
  16. P. Zinin, W. Weise, O. Lobkis, O. Kolosov, and S. Boseck, "Fourier optics analysis of spherical-particles image-formation in reflection acoustic microscopy," Optik (Stuttgart) 98, 45-60 (1994).
  17. B. Ovryn and S. H. Izen, "Imaging of transparent spheres through a planar interface using a high-numerical-aperture optical microscope," J. Opt. Soc. Am. A 17, 1202-1213 (2000). [CrossRef]
  18. C. J. R. Sheppard and T. Wilson, "Multiple traversing of the object in the scanning microscope," Opt. Acta 27, 611-624 (1980). [CrossRef]
  19. C. J. Cogswell and C. J. R. Sheppard, "Confocal brightfield imaging techniques using an on-axis scanning optical microscope," in Confocal Microscopy, T.Wilson, ed. (Academic, 1990), pp. 213-243.
  20. C. J. Cogswell and C. J. R. Sheppard, "Imaging using confocal brightfield techniques," in EMAG-Micro '89' (Institute of Physics, 1990), pp. 633-638.

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 
Fig. 4 Fig. 5
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited