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Journal of the Optical Society of America B

Journal of the Optical Society of America B

| OPTICAL PHYSICS

  • Editor: Henry M. Van Driel
  • Vol. 25, Iss. 7 — Jul. 1, 2008
  • pp: 1223–1230

Enhancement of laser radiation coupled into turbid media by using a unidirectional mirror

Pavel Matousek  »View Author Affiliations


JOSA B, Vol. 25, Issue 7, pp. 1223-1230 (2008)
http://dx.doi.org/10.1364/JOSAB.25.001223


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Abstract

This article analyzes a simple method for the enhancement of laser radiation coupled into deep layers of turbid samples. This is accomplished by using a multilayer dielectric bandpass filter that acts as a unidirectional mirror and reflects photons re-emerging from the sample back into it. The research establishes a theoretical framework, and a very basic feasibility study is performed. In this study, laser intensity, delivered through a 14 mm slab of tissue, and a 3.9 mm pharmaceutical tablet were enhanced by factors of 1.6 and 3.8, respectively. Potential applications include photothermal and photodynamic cancer therapies of subsurface tissue, deep optical spectroscopy and imaging of biological tissue and powders, as well as thermal and optical subsurface treatment of powder materials, colloids, and catalysts.

© 2008 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5180) Medical optics and biotechnology : Photodynamic therapy
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(290.1990) Scattering : Diffusion
(290.7050) Scattering : Turbid media
(350.3390) Other areas of optics : Laser materials processing

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 8, 2008
Revised Manuscript: April 17, 2008
Manuscript Accepted: April 21, 2008
Published: June 30, 2008

Virtual Issues
Vol. 3, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Pavel Matousek, "Enhancement of laser radiation coupled into turbid media by using a unidirectional mirror," J. Opt. Soc. Am. B 25, 1223-1230 (2008)
http://www.opticsinfobase.org/josab/abstract.cfm?URI=josab-25-7-1223


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References

  1. H. Wang, D. W. Brandl, F. Le, P. Nordlander, and N. J. Halas, “Nanorice: A hybrid plasmonic nanostructure,” Int. Chem. Eng. 6, 827-832 (2006).
  2. X. H. Huang, I. H. El-Sayed, W. Qian, and M. A. El-Sayed, “Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods,” J. Am. Chem. Soc. 128, 2115-2120 (2006). [CrossRef] [PubMed]
  3. L. H. V. Wang, R. E. Nordquist, and W. R. Chen, “Optimal beam size for light delivery to absorption-enhanced tumors buried in biological tissues and effect of multiple-beam delivery: A Monte Carlo study,” Am. J. Optom. Physiol. Opt. 36, 8286-8291 (1997).
  4. P. Matousek, “Raman signal enhancement in deep spectroscopy of turbid media,” Appl. Spectrosc. 61, 845-854 (2007). [CrossRef]
  5. P. Kubelka and F. Munk, “Ein beitrag zur optik der farbanstriche,” Z. Tech. Phys. (Leipzig) 12, 593-601 (1931).
  6. B. Schrader and G. Bergmann, “Die Intensitat des Ramanspektrums polykristalliner Substanzen,” Fresenius' Z. Anal. Chem. 225, 230-247 (1967). [CrossRef]
  7. B. Schrader and D. S. Moore, “Laser based molecular spectroscopy for chemical analysis--Raman scattering process,” Pure Appl. Chem. 69, 1451-1468 (1997). [CrossRef]
  8. B. B. Das, F. Liu, and R. R. Alfano, “Time-resolved fluorescence and photon migration studies in biomedical and model random media,” Rep. Prog. Phys. 60, 227-292 (1997). [CrossRef]
  9. G. Mitic, J. Kolzer, J. Otto, E. Plies, G. Solkner, and W. Zinth, “Time-gated transillumination of biological tissues and tissuelike phantoms,” Am. J. Optom. Physiol. Opt. 33, 6699-6710 (1994).
  10. N. Everall, T. Hahn, P. Matousek, A. W. Parker, and M. Towrie, “Picosecond time-resolved Raman spectroscopy of solids: Capabilities and limitations for fluorescence rejection and the influence of diffuse reflectance,” Appl. Spectrosc. 55, 1701-1708 (2001). [CrossRef]
  11. N. Everall, T. Hahn, P. Matousek, A. W. Parker, and M. Towrie, “Photon migration in Raman spectroscopy,” Appl. Spectrosc. 58, 591-597 (2004). [CrossRef]
  12. M. Born and E. Wolf, Principles of Optics, 7th ed. (Cambridge University Press, 2005).
  13. J. C. Henderson, Q. Su, and R. Grobe, “Mirror assisted imaging in one-dimensional turbid media using photon density waves,” Laser Phys. 14, 515-520 (2004).
  14. C. J. H. Brenan and I. W. Hunter, “Volumetric Raman microscopy through a turbid medium,” J. Raman Spectrosc. 27, 561-570 (1996). [CrossRef]
  15. P. Matousek and N. Stone, “Prospects for the diagnosis of breast cancer by noninvasive probing of calcifications using transmission Raman spectroscopy,” J. Biomed. Opt. 12, 024008 (2007). [CrossRef]

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