This study reports a portable and precision photonic biosensor reader that can measure the concentration of a particular antigen using an optical resonant reflection biosensor (ORRB). To create a compact biosensor reader, a compact tunable vertical-cavity surface-emitting laser (VCSEL) and a compact built-in wavelength meter were manufactured. The wavelength stability and accuracy of the compact built-in wavelength meter were measured to be less than 0.02 nm and 0.06 nm, respectively. The tunable VCSEL emission wavelength was measured with the compact built-in wavelength meter, it has a fast sweep time (~ 10 seconds) and a wide tuning range (> 4 nm) that are sufficient for biosensor applications based on ORRB. The reflection spectrum of a plastic based ORRB chip was measured by the fabricated portable photonic biosensor reader using the VCSEL and wavelength meter. Although the reader is the size of a palmtop device, it could make a precise measurement of the peak wavelength on equal terms with a conventional bulky optical spectrometer.
© 2010 Optical Society of Korea
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(140.3600) Lasers and laser optics : Lasers, tunable
(300.6260) Spectroscopy : Spectroscopy, diode lasers
(280.1415) Remote sensing and sensors : Biological sensing and sensors
Original Manuscript: May 13, 2010
Revised Manuscript: August 18, 2010
Manuscript Accepted: September 7, 2010
Published: December 25, 2010
Hyun-Sung Ko, Bong-Kyu Kim, Kyung-Hyun Kim, Chul Huh, Wan-Joong Kim, Jong-Cheol Hong, Seon-Hee Park, Seong-Seok Yang, Ho-Jin Jang, and Gun-Yong Sung, "A Compact Tunable VCSEL and a Built-in Wavelength Meter for a Portable Optical Resonant Reflection Biosensor Reader," J. Opt. Soc. Korea 14, 395-402 (2010)
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