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Journal of the Optical Society of Korea

Journal of the Optical Society of Korea


  • Vol. 15, Iss. 3 — Sep. 1, 2011
  • pp: 300–304

Design and Fabrication of a Multi-modal Confocal Endo-Microscope for Biomedical Imaging

Young-Duk Kim, Myoung-Ki Ahn, and Dae-Gab Gweon  »View Author Affiliations

Journal of the Optical Society of Korea, Vol. 15, Issue 3, pp. 300-304 (2011)

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Optical microscopes are widely used for medical imaging these days, but biopsy is a lengthy process that causes many problems during the ex-vivo imaging procedure. The endo-microscope has been studied to increase accessibility to the human body and to get in-vivo images to use for medical diagnosis. This research proposes a multi-modal confocal endo-microscope for bio-medical imaging. We introduce the design process for a small endoscopic probe and a coupling mechanism for the probe to make the multi-modal confocal endo-microscope. The endoscopic probe was designed to decrease chromatic and spherical aberrations, which deteriorate the images obtained with the conventional GRIN lens. Fluorescence and reflectance images of various samples were obtained with the proposed endo-microscope. We evaluated the performance of the proposed endo-microscope by analyzing the acquired images, and demonstrate the possibilities of in-vivo medical imaging for early diagnosis.

© 2011 Optical Society of Korea

OCIS Codes
(110.2350) Imaging systems : Fiber optics imaging
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(220.4830) Optical design and fabrication : Systems design

Original Manuscript: April 4, 2011
Revised Manuscript: August 9, 2011
Manuscript Accepted: August 9, 2011
Published: September 25, 2011

Young-Duk Kim, Myoung-Ki Ahn, and Dae-Gab Gweon, "Design and Fabrication of a Multi-modal Confocal Endo-Microscope for Biomedical Imaging," J. Opt. Soc. Korea 15, 300-304 (2011)

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