Using continuous wave near-infrared spectroscopy, we measured time-resolved concentration changes of oxy-hemoglobin and deoxy-hemoglobin from the primary motor cortex following finger tapping tasks. These data were processed using partial least squares-discriminant analysis (PLS-DA) to develop a prediction model for a brain-computer interface. The tasks were composed of a series of finger tapping for 15 sec and relaxation for 45 sec. The location of the motor cortex was confirmed by the anti-phasic behavior of the oxy- and deoxy-hemoglobin changes. The results were compared with those obtained using the hidden Markov model (HMM) which has been known to produce the best prediction model. Our data imply that PLS-DA makes better judgments in determining the onset of the events than HMM.
© 2012 Optical Society of Korea
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging
Original Manuscript: October 12, 2011
Revised Manuscript: December 19, 2011
Manuscript Accepted: December 26, 2011
Published: March 25, 2012
Young-Wook Seo, Seung-Duk Lee, Dal-Kwon Koh, and Beop-Min Kim, "Partial Least Squares-discriminant Analysis for the Prediction of Hemodynamic Changes Using Near Infrared Spectroscopy," J. Opt. Soc. Korea 16, 57-62 (2012)
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