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Journal of the Optical Society of Korea

Journal of the Optical Society of Korea

| PUBLISHED BY THE OPTICAL SOCIETY OF KOREA

  • Vol. 18, Iss. 2 — Apr. 1, 2014
  • pp: 151–155

Array-Based Real-Time Ultrasound and Photoacoustic Ocular Imaging

Seung Yun Nam and Stanislav Y. Emelianov  »View Author Affiliations


Journal of the Optical Society of Korea, Vol. 18, Issue 2, pp. 151-155 (2014)


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Abstract

Although various ophthalmic imaging methods, including fundus photography and optical coherence tomography, have been applied for effective diagnosis of ocular diseases with high spatial resolution, most of them are limited by shallow imaging penetration depth and a narrow field of view. Also, many of those imaging modalities are optimized to provide microscopic anatomical information, while functional or cellular information is lacking. Compared to other ocular imaging modalities, photoacoustic imaging can achieve relatively deep penetration depth and provide more detailed functional and cellular data based on photoacoustic signal generation from endogenous contrast agents such as hemoglobin and melanin. In this paper, array-based ultrasound and photoacoustic imaging was demonstrated to visualize pigmentation in the eye as well as overall ocular structure. Fresh porcine eyes were visualized using a real-time ultrasound micro-imaging system and an imaging probe supporting laser pulse delivery. In addition, limited photoacoustic imaging field of view was improved by an imaging probe tilting method, enabling visualization of most regions of the retina covered in the ultrasound imaging.

© 2014 Optical Society of Korea

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(110.7170) Imaging systems : Ultrasound
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4470) Medical optics and biotechnology : Ophthalmology
(110.5125) Imaging systems : Photoacoustics

History
Original Manuscript: March 13, 2014
Revised Manuscript: March 20, 2014
Manuscript Accepted: March 20, 2014
Published: April 25, 2014

Citation
Seung Yun Nam and Stanislav Y. Emelianov, "Array-Based Real-Time Ultrasound and Photoacoustic Ocular Imaging," J. Opt. Soc. Korea 18, 151-155 (2014)
http://www.opticsinfobase.org/josk/abstract.cfm?URI=josk-18-2-151


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