OSA's Digital Library

Journal of the Optical Society of Korea

Journal of the Optical Society of Korea


  • Vol. 7, Iss. 4 — Dec. 25, 2003
  • pp: 234–239

Polarization Spectral Imaging System for Quantitative Evaluation of Port Wine Stain Blanching Following Laser Treatment

Byung-Jo Jung  »View Author Affiliations

Journal of the Optical Society of Korea, Vol. 7, Issue 4, pp. 234-239 (2003)

View Full Text Article

Acrobat PDF (502 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

  • Export Citation/Save Click for help


Objective methods to assess quantitatively port wine stain (PWS) blanching in response to laser therapy are needed to improve laser therapeutic outcome. Previous studies have attempted to assess objectively PWS color based on point measurement devices. To date, these approaches have typically been limited by a number of factors such as small test area and need for contact. To address these issues, a polarization spectral imaging system and an image analysis method have been developed to evaluate quantitatively erythema and melanin content distribution in skin. The developed polarization spectral imaging system minimizes artifacts such as glaring, shadowing, and non-uniform illumination that interfere with image fidelity. Furthermore, the image analysis method has been employed to get images of skin melanin and erythema indices from the acquired color images for quantitative analysis. Finally, using PWS patient color image, the effectiveness in laser treatment of PWS was evaluated by calculating relative erythema index image that is the relative erythema index of PWS region to the normal region. The developed device and analysis method appears to be a simple and effective method for quantitative analysis of PWS blanching.

© 2003 Optical Society of Korea

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.1870) Medical optics and biotechnology : Dermatology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

Original Manuscript: September 24, 2003
Published: December 1, 2003

Byung-Jo Jung, "Polarization Spectral Imaging System for Quantitative Evaluation of Port Wine Stain Blanching Following Laser Treatment," J. Opt. Soc. Korea 7, 234-239 (2003)

Sort:  Year  |  Journal  |  Reset


  1. J. S. Nelson, K. M. Kelly, Y. Zhao, Z. Chen, "Imaging blood flow in human port-wine stain in situ and in real time using optical doppler tomography," Arch. Dermatol., vol. 137, no. 6, pp. 741-744, 2001
  2. K. Onizuka, K. Tsuneda, Y. Shibata, M. Ito, I. Sekine, "Efficacy of flashlamp-pumped pulse dye laser for port wine stains: clinical assessment and histopathological characteristics," Brit. J. Plast. Surg., vol. 48, no. 5, pp. 271-279, 1995 [CrossRef]
  3. P. H. L. Koster, C. M. A. M. van der Horst, O. M. M. Bossuyt, M. J. C. van Gemert, "Prediction of portwine stain clearance and required number of flashlamp pumped dye laser treatments," Lasers Surg. Med., vol. 29, pp. 151-155, 2001 [CrossRef]
  4. S. Michel, M. Landthaler, U. Hohenleutner, "Recurrence of port-wine stains after treatment with the flashlamp-pumped pulsed dye laser," Brit. J. Dermatol., vol. 143, no. 6, pp. 1230-1234, 2000 [CrossRef]
  5. O. T. Tan, K. Sherwood, B. A. Gilchrest, "Treatment of children with port-wine stains using the flashlamppulsed tunable dye laser," New Engl. J. Med., vol. 320, no. 7, pp. 416-421, 1989
  6. M. Haederdsal, H. Efsen, M. Gniadecka, H. Fogh, J. Keiding, H.C. Wulf, "Changes in skin redness, pig-mentation, echostructure, thickness, and surface contour after 1 pulsed dye laser treatment of port-wine stains in children," Arch. Dermatol., vol. 134, no. 2, pp.175-181, 1998 [CrossRef]
  7. M. J. C. van Gemert, J. S. Nelson, T. E. Milner, D. J. Smithies, W. Verkruysse, J. F. de Boer, G. W. Lucassen, D. M. Goodman, B. S. Tanenbaum, L. T. Norvang, L. O. Svaasand, "Noninvasive determination of port wine stain anatomy and physiology for optimal laser treatment strategies," Phys. Med. Biol., vol. 42, no. 5, pp. 937-950, 1997 [CrossRef]
  8. K. T. Le, J. Shahidullah, I. J. Frienden, "Review of modern techniques in detecting port-wine stain response to laser therapy," Dermatol. Surg., vol. 25, no. 2, pp. 127-132, 1999 [CrossRef]
  9. A. M. Troilius, B. Ljunggren, "Reflectance spectrophotometry in the objective assessment of dye laser-treated port-wine stains," Brit. J. Dermatol., vol. 132, no. 2, pp. 245-250, 1995 [CrossRef]
  10. A. M. Troilius, B. Ljunggren, "Evaluation of port wine stains by Laser Doppler perfusion imaging and reflectance photometry before and after pulsed dye laser treatment," Acta. Derm. Venereol., vol. 76, no. 4, pp. 291-294, 1996
  11. E. Berardesca, P. Elsner, K-P Wilhelm, H.I. Maibach, Bioengineering of the skin: Methods and Instrumentation (CRC Press, Boca Raton, FL, 1995), pp. 29-40
  12. M. D. Shriver, E. Parra, "Comparison of narrow-band reflectance spectroscopy and tristimulus colorimetry of measurements of skin and hair color in persons of different biological ancestry," Am. J. Phys. Anthropol., vol. 112, no. 1, pp. 17-27, 2000 [CrossRef]
  13. H. Takiwaki, S. Shirai, Y. Kanno, Y. Watanabe, S. Arase, "Quantification of erythema and pigmentation using a videomicroscope and computer," Brit. J. Dermatol., vol. 131, no. 1, pp. 85-92, 1984 [CrossRef]
  14. P. Clarys, K. Alewaeters, R. Lambrecht, A. O. Barel, "Skin color measurements: comparison between three instruments: the Chromameter, the DermaSpectrometer and the Mexameter," Skin Res. Technol., vol. 6, no. 6, pp. 230-238, 2000 [CrossRef]
  15. W. Alaluf, D. Atkins, K. Barrett, M. Blount, N. Carter, A. Heath, "The impact of epidermal melanin on objective measurements of human skin color," Pigment Cell Res., vol. 15, no. 2, pp. 119-126, 2002 [CrossRef]
  16. A. O. Barel, P. Clarys, K. Alewaeters, C. Duez, J. L. Hubinon, M. Mommaerts, "The Visi-Chroma VC-100: a new imaging colorimeter for dermatocosmetic research," Skin Res. Technol., vol. 7, no. 1, pp. 24-31, 2001 [CrossRef]
  17. H. Takiwaki, Y. Miyaoka, N. Skrebova, H. Kohno, S. Arase, "Skin reflectance-spectra and colour-value dependency on measuring-head aperture area in ordinary reflectance spectrophotometry and tristimulus colourimetry," Skin Res. Technol., vol. 8, no. 2, pp. 94-97, 2002 [CrossRef]
  18. J. K. Wagner, C. Jovel, H. L. Norton, E. J. Parra, M. D. Shirver, "Comparing quantitative measures of erythema, pigmentation and skin response using reflectometry," Pigment Cell Res., vol 15, no. 5, pp. 379-384, 2002 [CrossRef]
  19. H. Takiwaki, Y. Miyaoka, H. Kohno, S. Arase, "Graphic analysis of the relationship between skin colour change and variations in the amounts of melanin and hemoglobin," Skin Res. Technol., vol. 8, no. 2, pp. 78-83, 2002 [CrossRef]
  20. M. Seraro, A. Sparavigna, "Quantification of erythema using digital camera and computer-based image analysis: a multicentre study," Skin Res. Technol., vol. 8, no. 2, pp. 84-88, 2002 [CrossRef]
  21. S. A. Young-Gee, H. A. Kurwa, R. J. Barlow, "Objective assessment of port-wine stains following treatment with the 585nm pulsed dye laser," Aust. J. Dermatol., vol. 42, no. 4, pp. 243-246, 2001 [CrossRef]
  22. K. Miyamoto, H. Takiwaki, G. G. Hillebrand, S. Arase, "Utilization of a high-resolution digital imaging system for the objective and quantitative assessment of hyperpigmented spots on the face," Skin Res. Technol., vol. 8, no. 2, pp. 73-77, 2002 [CrossRef]
  23. D. K. Rah, S. H. Kim, K. H. Lee, B. Y. Park, D. W. Kim, "Objective evaluation of treatment effects on port-wine stains using <TEX>${L^*a^*b^*}$</TEX> color coordinate," Plast. Reconstr. Surg., vol. 108, no. 4, pp. 842-847, 2001 [CrossRef]
  24. B. L. Diffey, R. J. Oliver, P. M. Farr, "A portable instrument for quantifying erythema induced by ultraviolet radiation," Brit. J. Dermatol., vol. 111, no. 6, pp. 663-672, 1984 [CrossRef]
  25. P. M. Farr, B. L. Diffey, "Quantitative studies on cutaneous erythema induced by ultraviolet radiation," Brit. J. Dermatol., vol. 111, no. 6, pp. 673-682, 1984 [CrossRef]
  26. J. B. Dawson, D. J. Barker, D. J. Ellis, "A theoretical and experimental study of light absorption and scattering by in vivo skin," Phys. Med. Biol., vol. 25, no. 4, pp. 695-709, 1980 [CrossRef]

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited