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Journal of Optical Technology

Journal of Optical Technology


  • Vol. 75, Iss. 12 — Dec. 1, 2008
  • pp: 772–777

Illuminator for photodynamic therapy and fluorescence diagnosis with lightguide output of the radiation

Kang Uk, D. A. Makarov, Lee Seung Yup, Bae Su Jin, and G. V. Papayan  »View Author Affiliations

Journal of Optical Technology, Vol. 75, Issue 12, pp. 772-777 (2008)

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Mercury and halogen lamps that possess mutually supplementary spectral responses are used simultaneously in an illuminator intended for phototherapy and fluorescence diagnosis. Their radiation is summed and delivered to an object through a liquid lightguide. Two summation methods--spectral and angular--are tested experimentally. The best results are given by the latter method, in which convergent beams from the lamps are directed into the lightguide at different angles. The total optical power at the lightguide output is 14.5W in the 300-800-nm range. The working spectral interval is selected by means of switchable interference filters on command from a built-in processor. The influence of the spectral width of the radiation on the efficiency with which the radiant flux is used is estimated.

© 2008 Optical Society of America

Kang Uk, D. A. Makarov, Lee Seung Yup, Bae Su Jin, and G. V. Papayan, "Illuminator for photodynamic therapy and fluorescence diagnosis with lightguide output of the radiation," J. Opt. Technol. 75, 772-777 (2008)

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  1. T. J. Dougherty, C. J. Gomer, B. W. Henderson, G. Jori, D. Kessel, M. Korbelik, J. Moan, and Q. Peng, “Photodynamic therapy,” J. Natl. Cancer Inst. 90, 889 (1998). [CrossRef]
  2. M. Leonhard, “New incoherent autofluorescence/fluorescence system for early detection of lung cancer,” Diag. Therap. Endos. 5, 71 (1999).
  3. G. V. Papayan and Kang Uk, “Fluorescence endoscopic video system,” Opt. Zh. 64, No. 10, 94 (2006) G. V. Papayan and Kang Uk[J. Opt. Technol. 64, 739 (2006)].
  4. J. Hewett, V. Nadeau, J. Ferguson, H. Moseley, S. Ibbotson, J. W. Allen, W. Sibbett, and M. Padgett, “The application of compact multispectral imaging system with integrated excitation source to in-vivo monitoring of fluorescence during topical photodynamic therapy of superficial skin cancer,” Photochem. Photobiol. 73, No. 30, 278 (2001). [CrossRef]
  5. Kang Uk, G. V. Papayan, Bae Soo-Jin, V. B. Berezin, and S. Kim, “Fluorescence video dermatoscope,” Opt. Zh. 75, No. 1, 32 (2008) Kang Uk, G. V. Papayan, Bae Soo-Jin, V. B. Berezin, and S. Kim[J. Opt. Technol. 75, 24 (2008)].
  6. R. Richards-Kortum and E. Sevick-Muraca, “Quantitative optical spectroscopy for tissue diagnosis,” Annu. Rev. Phys. Chem. 47, No. 1, 555 (1996). [CrossRef]
  7. G. A. Wagnieres, W. M. Star, and B. C. Wilson, “In-vivo fluorescence spectroscopy and imaging for oncological applications,” Photochem. Photobiol. 68, 603 (1998). [CrossRef]
  8. G. V. Papayan and I. Ya. Barsky, “Contact luminescence spectrophotometry for biomedical studies,” Proc. SPIE 4515, 125 (2001). [CrossRef]
  9. V. I. Karandashov, E. B. Petukhov, and V. S. Zrodnikov, Phototherapy (Light Therapy) (ed.) N.R.Paleeva (Meditisina, Moscow, 2001).
  10. Kang Uk, G. Papayan, Bae Soo Jin, and Rim Geun Hie, “Light source for fluorescence diagnosis and photodynamic therapy,” Patent KR10-0798486.
  11. Kang Uk, G. Papayan, D. Makarov, Lee Seung Yup, and Bae Soo Jin, “Light-source system for phototherapy of skin disease,” Patent appl. KR20070101398.
  12. P. Papageorgiou, A. Katsambas, and A. Chu, “Phototherapy with blue (415nm) and red (660nm) light in the treatment of acne vulgaris,” British J. Dermat. No. 142, 973 (2000).

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