OSA's Digital Library

Journal of Optical Technology

Journal of Optical Technology

| SIMULTANEOUS RUSSIAN-ENGLISH PUBLICATION

  • Vol. 80, Iss. 1 — Jan. 1, 2013
  • pp: 40–48

Spectrometer for fluorescence–reflection biomedical research

Kang Uk, V. B. Berezin, G. V. Papayan, N. N. Petrishchev, and M. M. Galagudza  »View Author Affiliations


Journal of Optical Technology, Vol. 80, Issue 1, pp. 40-48 (2013)
http://dx.doi.org/10.1364/JOT.80.000040


View Full Text Article

Acrobat PDF (1498 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

A fluorescence–reflection multichannel fiber spectrometer has been developed that makes it possible to carry out a wide range of biomedical research, including estimating the concentration of glycation end-products in the skin and the oxidation–reduction state of various tissues. It has the feature of being able to simultaneously record diffuse reflection spectra and fluorescence emission. The fluorescence is excited by an LED that emits at 365 nm. The fluorescence spectra are recorded in the 400–750 nm region, while the reflection spectra are recorded in the 350–750 nm region. The convergence of the results of the measurements is 1.6%. A technique is proposed for correcting the autofluorescence index of the skin that makes it possible to sharply reduce its dependence on the degree of skin pigmentation. The possibilities of the device are illustrated by examples of biomedical research.

© 2013 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

History
Original Manuscript: September 4, 2012
Published: January 1, 2013

Citation
Kang Uk, V. B. Berezin, G. V. Papayan, N. N. Petrishchev, and M. M. Galagudza, "Spectrometer for fluorescence–reflection biomedical research," J. Opt. Technol. 80, 40-48 (2013)
http://www.opticsinfobase.org/jot/abstract.cfm?URI=jot-80-1-40

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited