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Journal of Optical Technology

Journal of Optical Technology


  • Vol. 80, Iss. 9 — Sep. 1, 2013
  • pp: 566–570

Mathematical modelling of signals recorded in noninvasive medical laser fluorescence diagnosis

D. A. Rogatkin and O. D. Smirnova  »View Author Affiliations

Journal of Optical Technology, Vol. 80, Issue 9, pp. 566-570 (2013)

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Based on the Kubelka–Munk two-flux model modified by the authors, which makes it possible in one-dimensional problems to obtain exact analytical expressions for radiation fluxes at the boundary of a turbid medium, and Kokhanovsky’s solution for the radiation flux of fluorescence, questions are considered of modelling the spectrum of stimulated endogenous fluorescence of biological tissues as applied to problems of noninvasive medical diagnosis. An analytical expression is presented for the spectral distortion function, which depends on the scattering and absorption properties of cellular biological tissues and blood. It is shown that the model spectra agree well with the experimental data.

© 2013 Optical Society of America

OCIS Codes
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

Original Manuscript: January 21, 2013
Published: November 27, 2013

D. A. Rogatkin and O. D. Smirnova, "Mathematical modelling of signals recorded in noninvasive medical laser fluorescence diagnosis," J. Opt. Technol. 80, 566-570 (2013)

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