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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 12, Iss. 19 — Sep. 20, 2004
  • pp: 4390–4398

Optical trapping, manipulation, and sorting of cells and colloids in microfluidic systems with diode laser bars

Robert W. Applegate, Jr., Jeff Squier, Tor Vestad, John Oakey, and David W. M. Marr  »View Author Affiliations

Optics Express, Vol. 12, Issue 19, pp. 4390-4398 (2004)

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We demonstrate a new technique for trapping, sorting, and manipulating cells and micrometer-sized particles within microfluidic systems, using a diode laser bar. This approach overcomes the scaling limitations of conventional scanned laser traps, while avoiding the computational and optical complexity inherent to holographic optical trapping schemes. The diode laser bar enables us to control a large trapping zone, 1 μm by 100 μm, without the necessity of scanning or altering the phase of the beam.

© 2004 Optical Society of America

OCIS Codes
(140.2020) Lasers and laser optics : Diode lasers
(140.5960) Lasers and laser optics : Semiconductor lasers
(140.7010) Lasers and laser optics : Laser trapping
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.0180) Medical optics and biotechnology : Microscopy
(170.1530) Medical optics and biotechnology : Cell analysis
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.4520) Medical optics and biotechnology : Optical confinement and manipulation

ToC Category:
Research Papers

Original Manuscript: August 13, 2004
Revised Manuscript: September 3, 2004
Published: September 20, 2004

Robert Applegate, Jr., Jeff Squier, Tor Vestad, John Oakey, and David Marr, "Optical trapping, manipulation, and sorting of cells and colloids in microfluidic systems with diode laser bars," Opt. Express 12, 4390-4398 (2004)

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