Full-color three-dimensional microscopy by wide-field optical coherence tomography
Optics Express, Vol. 12, Issue 26, pp. 6632-6641 (2004)
http://dx.doi.org/10.1364/OPEX.12.006632
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Abstract
We demonstrate a method of optical tomography for surface and sub-surface imaging of biological tissues, based on the principle of wide field optical coherence tomography and capable of providing full-color three-dimensional views of a tissue structure. Contour or tomographic images are obtained with an interferometric imaging system using broadband light sources. The interferometric images are analyzed in the three color channels and recombined to generate 3D microscopic images of tissue structures with full natural color representation. In contrast to most existing three-dimensional microscopy methods, the presented technique allows monitoring of tissue structures close to its natural color, which may be useful in physiological and pathological applications.
© 2004 Optical Society of America
OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(180.6900) Microscopy : Three-dimensional microscopy
ToC Category:
Research Papers
History
Original Manuscript: November 3, 2004
Revised Manuscript: December 14, 2004
Published: December 27, 2004
Citation
Lingfeng Yu and M. Kim, "Full-color three-dimensional microscopy by wide-field optical coherence tomography," Opt. Express 12, 6632-6641 (2004)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-12-26-6632
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