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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 1, Iss. 13 — Dec. 22, 1997
  • pp: 414–423

An approach to the synthesis of biological tissue

Jannick P. Rolland and Robin N. Strickland  »View Author Affiliations

Optics Express, Vol. 1, Issue 13, pp. 414-423 (1997)

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Mathematical phantoms developed to synthesize realistic complex backgrounds such as those obtained when imaging biological tissue, play a key role in the quantitative assessment of image quality for medical and biomedical imaging. We present a modeling framework for the synthesis of realistic tissue samples. The technique is demonstrated using radiological breast tissue. The model employs a two-component image decomposition consisting of a slowly, spatially varying mean-background and a residual texture image. Each component is synthesized independently. The approach and results presented here constitute an important step towards developing methods for the quantitative assessment of image quality in medical and biomedical imaging, and more generally image science.

© Optical Society of America

OCIS Codes
(100.0100) Image processing : Image processing
(170.3830) Medical optics and biotechnology : Mammography

ToC Category:
Focus Issue: Biomedical optics

Original Manuscript: October 20, 1997
Revised Manuscript: October 11, 1997
Published: December 22, 1997

Jannick Rolland and Robin Strickland, "An approach to the synthesis of biological tissue," Opt. Express 1, 414-423 (1997)

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