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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 11, Iss. 19 — Sep. 22, 2003
  • pp: 2416–2424

High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts

Victor X.D. Yang, Maggie L. Gordon, Shou-jiang Tang, Norman E. Marcon, Geoffrey Gardiner, Bing Qi, Stuart Bisland, Emily Seng-Yue, Stewart Lo, Julius Pekar, Brian C. Wilson, and I. Alex Vitkin  »View Author Affiliations


Optics Express, Vol. 11, Issue 19, pp. 2416-2424 (2003)
http://dx.doi.org/10.1364/OE.11.002416


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Abstract

We previously described a fiber based Doppler optical coherence tomography system [1] capable of imaging embryo cardiac blood flow at 4~16 frames per second with wide velocity dynamic range [2]. Coupling this system to a linear scanning fiber optical catheter design that minimizes friction and vibrations, we report here the initial results of in vivo endoscopic Doppler optical coherence tomography (EDOCT) imaging in normal rat and human esophagus. Microvascular flow in blood vessels less than 100 µm diameter was detected using a combination of color-Doppler and velocity variance imaging modes, during clinical endoscopy using a mobile EDOCT system.

© 2003 Optical Society of America

OCIS Codes
(100.6950) Image processing : Tomographic image processing
(110.4500) Imaging systems : Optical coherence tomography
(170.1650) Medical optics and biotechnology : Coherence imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Research Papers

History
Original Manuscript: July 21, 2003
Revised Manuscript: September 6, 2003
Published: September 22, 2003

Citation
Victor X. D. Yang, Maggie Gordon, Shou-jiang Tang, Norman Marcon, Geoffrey Gardiner, Bing Qi, Stuart Bisland, Emily Seng-Yue, Stewart Lo, Julius Pekar, Brian Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts," Opt. Express 11, 2416-2424 (2003)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-11-19-2416


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References

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