OSA's Digital Library

Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 12, Iss. 19 — Sep. 20, 2004
  • pp: 4596–4601

Particle aggregation monitoring by speckle size measurement; application to blood platelets aggregation

Y. Piederriere, J. Le Meur, J. Cariou, J.F. Abgrall, and M.T. Blouch  »View Author Affiliations


Optics Express, Vol. 12, Issue 19, pp. 4596-4601 (2004)
http://dx.doi.org/10.1364/OPEX.12.004596


View Full Text Article

Enhanced HTML    Acrobat PDF (101 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We report on a new method based on speckle size analysis and devoted to particle aggregation measurements. The experimental measurements give the speckle size variation during a salt aggregation process of polystyrene microspheres. The measurements are taken at a fixed monomer concentration, varying the salt concentration. Moreover, we applied this technique to follow blood platelet aggregation, usually monitored with a visible light transmittance photometer (aggregometer). Aggregation process was induced by ADP (adenosine diphosphate) addition, then we measured the speckle size variation versus time at two different ADP concentrations.

© 2004 Optical Society of America

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(290.5850) Scattering : Scattering, particles

ToC Category:
Research Papers

History
Original Manuscript: July 26, 2004
Revised Manuscript: August 23, 2004
Published: September 20, 2004

Citation
Yann Piederrière, J. Le Meur, J. Cariou, J. Abgrall, and M. Blouch, "Particle aggregation monitoring by speckle size measurement; application to blood platelets aggregation," Opt. Express 12, 4596-4601 (2004)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-12-19-4596


Sort:  Journal  |  Reset  

References

  1. J.P. Wilcoxon, J.E. Martin, D.W. Shaefer, �??Aggregation in colloidal gold,�?? Phys. Rev. A 39, 2675-2688 (1989). [CrossRef] [PubMed]
  2. M. Carpinetti, F. Ferri, M. Giglio, E. Paganini, U. Perini, �??Salt-induced fast aggregation of polystyrene latex,�?? Phys. Rev. A 42, 7347-7354 (1990). [CrossRef]
  3. Y. Georgalis, E.B. Starikov, B. Hollenbach, R. Lurz, Eberhard Scherzinger, W. Sger, H. Lehrach, E. Wanker, �??Huntingtin aggregation monitored by dynamic light scattering,�?? Proc. Natl. Acad. Sci. 95, 6118-6121 (1998). [CrossRef] [PubMed]
  4. D. Majolino, F. Mallamace, P. Migliardo, N. Micali, C. Vasi, �??Elastic and quasielastic light-scattering studies of the aggregation phenomena in water solutions of polystyrene particles,�?? Phys. Rev. A 40, 4665-4674 (1989). [CrossRef] [PubMed]
  5. D.A. Boas and A. G. Yodh, �??Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,�?? J. Opt. Soc. Am. A 14, 192-215 (1997). [CrossRef]
  6. J.W. Goodman, �??Statistical Properties of Laser Speckle Patterns,�?? in Laser speckle and related phenomena, Vol. 9 in series Topics in Applied Physics, J.C. Dainty, Ed., (Springer-Verlag, Berlin, Heidelberg New York Tokyo, 1984).
  7. P. Lehmann, �??Surface-roughness measurement based on the intensity correlation function of scattered light under speckle-pattern illumination,�?? Appl. Opt. 38, 1144-1152 (1999). [CrossRef]
  8. G. Da Costa and J. Ferrari, �??Anisotropic speckle patterns in the light scattered by rough cylindrical surfaces,�?? Appl. Opt. 36, 5231-5237 (1997). [CrossRef] [PubMed]
  9. R. Berlasso, F. Perez Quintian, M.A. Rebollo, C.A. Raffo and N.G. Gaggioli, �??Study of speckle size of light scattered from cylindrical rough surfaces,�?? Appl. Opt. 39, 5811-5819 (2000). [CrossRef]
  10. A. Sadhwani, K.T. Schomaker, G.J. Tearney and N.S. Nishioka, �??Determination of Teflon thickness with laser speckle. I. Potential for burn depth diagnosis,�?? Appl. Opt. 35, 5727-5735 (1996). [CrossRef] [PubMed]
  11. Y. Ozaki, �??Measurement of platelet aggregation and attempts for standardization,�?? Sysmex J. Int. 8, 15-22 (1998).
  12. P. Latimer, �??Blood platelet aggrgometer: predicted effects of aggregation, photometer geometry, and multiple scattering,�?? Appl. Opt. 22, 1136-1143 (1983). [CrossRef] [PubMed]
  13. Y. Piederriere, J. Cariou, Y. Guern, B. Le Jeune, G. Le Brun, J. Lotrian, �??Scattering through fluids: speckle size measurement and Monte Carlo simulations close to and into the multiple scattering,�?? Opt. Express 12, 176-188 (2004), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-1-176">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-1-176</a> [CrossRef] [PubMed]
  14. H.C. Van de Hulst, Light scattering by small particles (New York, Dover, 1981).
  15. Terri L. Alexander, James E. Harvey, and Arthur R. Weeks, �??Average speckle size as a function of intensity threshold level: comparison of experimental measurements with theory,�?? Appl. Opt. 33, 8240-8250 (1994). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1. Fig.2. Fig.3.
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited