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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 12, Iss. 21 — Oct. 18, 2004
  • pp: 5198–5208

Wide-field retinal hemodynamic imaging with the tracking scanning laser ophthalmoscope

R. Daniel Ferguson, Daniel X. Hammer, Ann E. Elsner, Robert H. Webb, Stephen A. Burns, and John J. Weiter  »View Author Affiliations


Optics Express, Vol. 12, Issue 21, pp. 5198-5208 (2004)
http://dx.doi.org/10.1364/OPEX.12.005198


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Abstract

Real time, high-speed image stabilization with a retinal tracking scanning laser ophthalmoscope (TSLO) enables new approaches to established diagnostics. Large frequency range (DC to 19 kHz), wide-field (40-deg) stabilized Doppler flowmetry imaging was demonstrated in initial human subject tests. The fundus imaging method is a quasi-confocal line-scanning laser ophthalmoscope (LSLO). The retinal tracking system uses a confocal reflectometer with a closed loop optical servo system to lock onto features in the ocular fundus and automatically re-lock after blinks. By performing a slow scan with the laser line imager, frequency-resolved retinal perfusion and vascular flow images were obtained free of eye motion artifacts. Normal adult subjects and patients were tested with and without mydriasis to characterize flow imaging performance.

© 2004 Optical Society of America

OCIS Codes
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology

ToC Category:
Research Papers

History
Original Manuscript: August 31, 2004
Revised Manuscript: October 4, 2004
Published: October 18, 2004

Citation
R. Ferguson, Daniel Hammer, Ann Elsner, Robert Webb, Stephen Burns, and John Weiter, "Wide-field retinal hemodynamic imaging with the tracking scanning laser ophthalmoscope," Opt. Express 12, 5198-5208 (2004)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-12-21-5198


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