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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 13, Iss. 2 — Jan. 24, 2005
  • pp: 583–594

High speed full range complex spectral domain optical coherence tomography

Erich Götzinger, Michael Pircher, Rainer A. Leitgeb, and Christoph K. Hitzenberger  »View Author Affiliations


Optics Express, Vol. 13, Issue 2, pp. 583-594 (2005)
http://dx.doi.org/10.1364/OPEX.13.000583


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Abstract

We present a high speed full range spectral domain optical coherence tomography system. By inserting a phase modulator into the reference arm and recording of every other spectrum with a 90° phase shift (introduced by the phase modulator) we are able to distinguish between negative and positive optical path differences with respect to the reference mirror. A modified two-frame algorithm eliminates the problem of suppressing symmetric structure terms in the final image. To demonstrate the performance of our method we present images of the anterior chamber of the human eye in vivo recorded with an A-scan rate of 10000 depth profiles per second.

© 2005 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

ToC Category:
Research Papers

History
Original Manuscript: November 24, 2004
Revised Manuscript: January 12, 2005
Published: January 24, 2005

Citation
Erich Götzinger, Michael Pircher, Rainer Leitgeb, and Christoph Hitzenberger, "High speed full range complex spectral domain optical coherence tomography," Opt. Express 13, 583-594 (2005)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-2-583


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References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254 , 1178-1181 (1991) [CrossRef] [PubMed]
  2. A. F. Fercher and C. K. Hitzenberger, "Optical coherence tomography," Progress in Optics 44, 215-302 (2002) [CrossRef]
  3. A. F. Fercher, W. Drexler, C. K. Hitzenberger, and T. Lasser, "Optical coherence tomography-principles and applications," Rep. Prog. Physics 66, 239-303 (2003) [CrossRef]
  4. R. A. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of Fourier Domain vs. Time Domain optical coherence tomography," Opt. Express 11, 889-894 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889</a> [CrossRef] [PubMed]
  5. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal to noise ratio in spectral domain compared with time domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003) [CrossRef] [PubMed]
  6. M. A. Choma, M. V. Sarunic, C. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183-2189 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-18-2183">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-18-2183</a> [CrossRef] [PubMed]
  7. N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh speed spectral domain optical coherence tomography," Opt. Lett. 29, 480- 482 (2004) [CrossRef] [PubMed]
  8. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El- Zaiat, "Measurement of intraocular distances by backscattering spectral interferometry," Opt. Commun. 117, 43-48 (1995) [CrossRef]
  9. G. Häusler and M. W. Lindner, "Coherence radar and spectral radar - new tools for dermatological diagnosis," J. Biomed. Opt. 3, 21-31 (1998) [CrossRef]
  10. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002) [CrossRef] [PubMed]
  11. A. F. Fercher, R. Leitgeb, C. K. Hitzenberger, H. Sattmann, and M. Wojtkowski, "Complex spectral interferometry OCT," Proc. SPIE. 3564, 173-178 (1999) [CrossRef]
  12. M. Wojtkowski , A. Kowalczyk, R. Leitgeb, and A. F. Fercher, "Full range complex spectral optical coherence tomography technique in eye imaging," Opt. Lett. 27, 1415-1417 (2002) [CrossRef]
  13. P. Targowski, M. Wojtkowski, A. Kowalczyk, T. Bajraszewski, M. Szkulmowski, and I. Gorczynska, "Complex spectral OCT in human eye imaging in vivo," Opt. Commun. 229, 79-84 (2004) [CrossRef]
  14. R. A. Leitgeb, C. K. Hitzenberger, A. F. Fercher, and T. Bajraszewski, "Phase shifting algorithm to achieve high speed long depth range probing by frequency domain optical coherence tomography," Opt. Lett. 28, 2201-2003 (2003) [CrossRef] [PubMed]
  15. R. N. Bracewell, The Fourier transform and its applications, 3rd ed. (McGraw-Hill, New York, 2000)
  16. N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12, 367-376 (2004), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-3-367">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-3-367</a> [CrossRef] [PubMed]
  17. R. A. Leitgeb, W. Drexler, A. Unterhuber, B. Hermann, T. Bajraszewski, T. Le, A. Stingl, and A.F Fercher, "Ultrahigh resolution Fourier domain optical coherence tomography," Opt. Express 12, 2156-2165 (2004), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-10-2156">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-10-2156</a> [CrossRef] [PubMed]
  18. B. Cense, N. A. Nassif, T. C. Chen, M. C. Pierce, S. H. Yun, B. H. Park, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "Ultrahigh-resolution high speed retinal imaging using spectral-domain optical coherence tomography," Opt. Express 12, 2435-2447 (2004), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-11-2435">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-11-2435</a> [CrossRef] [PubMed]
  19. M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultra high resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12, 2404-2422 (2004), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-11-2404">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-11-2404</a> [CrossRef] [PubMed]
  20. A. G. Podoleanu, G. M. Dobre, D. J. Webb, and D. A. Jackson, "Coherence imaging by use of a Newton rings sampling function," Opt. Lett. 21, 1789-1791 (1996) [CrossRef] [PubMed]
  21. A. G. Podoleanu, G. M. Dobre, and D. A. Jackson, "En face coherence imaging using galvanometer scanner modulation," Opt. Lett. 23, 147-149 (1998) [CrossRef]
  22. S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Motion artifacts in optical coherence tomography with frequency domain ranging," Opt Express 12, 2977- 2998 (2004), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-13-2977">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-13-2977</a> [CrossRef] [PubMed]
  23. American National Standards Institute: "American National Standard for Safe Use of Lasers," ANSI Z136.1- 2000. Orlando, Laser Institute of America, 35-49 (2000).

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