Particle-fixed Monte Carlo model for optical coherence tomography
Optics Express, Vol. 13, Issue 6, pp. 2182-2195 (2005)
http://dx.doi.org/10.1364/OPEX.13.002182
Enhanced HTML
Acrobat PDF (384 KB)
Abstract
Optical Coherence Tomography (OCT) is a new technique mainly used in biomedical imaging. We present here a Particle-Fixed Monte Carlo (PFMC) simulation for OCT signal. In the PFMC model, the scattering particles of the sample are assumed to be temporarily fixed and randomly distributed in the simulation of the backscattered light. An efficient partitioning scheme is proposed to speed up this simulation process. The new model explains the exponential decay signal at the interfaces of different media layers observed in OCT experimental measurements.
© 2005 Optical Society of America
OCIS Codes
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(290.7050) Scattering : Turbid media
ToC Category:
Research Papers
History
Original Manuscript: February 8, 2005
Revised Manuscript: March 13, 2005
Published: March 21, 2005
Citation
Guanglei Xiong, Ping Xue, Jigang Wu, Qin Miao, Rui Wang, and Liang Ji, "Particle-fixed Monte Carlo model for optical coherence tomography," Opt. Express 13, 2182-2195 (2005)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-6-2182
Sort: Journal | Reset
References
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, �??Optical coherence tomography,�?? Science 254, 1178�??1181 (1991). [CrossRef] [PubMed]
- Z. Chen, T. E. Milner, D. Dave, and J. S. Nelson, �??Optical Doppler tomographic image of fluid flow velocity in highly scattering media,�?? Opt. Lett. 22, 64�??66 (1997). [CrossRef] [PubMed]
- G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. J. Weissman, J. F. Southern, and J. G. Fujimoto, �??Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography,�?? Opt. Lett. 21, 543�??545 (1996). [CrossRef] [PubMed]
- G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, �??High speed phase- and group-delay scanning with a gratingbased phase control delay line,�?? Opt. Lett. 22, 1811�??1813 (1997). [CrossRef]
- Y. Pan, R. Birngruber, J. Rosperich, and R. Engelhardt, �??Low-coherence optical tomography in turbid tissue: theoretical analysis,�?? Appl. Opt. 34, 6564�??6574 (1995). [CrossRef] [PubMed]
- J. M. Schmitt, and A. Knuttel, �??Model of optical coherence tomography of heterogeneous tissue,�?? J. Opt. Soc. Am. A 14, 1231�??1242 (1997). [CrossRef]
- D. J. Smithies, T. Lindmo, Z. Chen, J. S. Nelson, and T. E. Milner, �??Signal attenuation and localization in optical coherence tomography studied by Monte Carlo simulation,�?? Phys. Med. Biol. 43, 3025�??3044 (1998). [CrossRef] [PubMed]
- G. Yao, and L. V. Wang, �??Monte Carlo simulation of an optical coherence tomography signal in homogeneous turbid media,�?? Phys. Med. Biol. 44, 2307�??2320 (1999). [CrossRef] [PubMed]
- A. Tycho, T. M. Jørgensen, H. T. Yura, and P. E. Andersen, �??Derivation of a Monte Carlo method for modeling heterodyne detection in optical coherence tomography systems,�?? Appl. Opt. 41, 6676�??6691 (2002). [CrossRef] [PubMed]
- P. E. Andersen, L. Thrane, H. T. Yura, A. Tycho, T. M. Jørgensen, and M. H. Frosz, �??Advanced modelling of optical coherence tomography systems,�?? Phys. Med. Biol. 49, 1307�??1327 (2004). [CrossRef] [PubMed]
- Q. Lu, X. Gan, M. Gu, and Q. Luo, �??Monte Carlo modeling of optical coherence tomography imaging through turbid media,�?? Appl. Opt. 43, 1628�??1637 (2004). [CrossRef] [PubMed]
- Y. Chen, P. Xue, T. Yuan, W. Chen, and D. Chen, �??Simulation of light scattering in optical coherence tomography,�?? Acta Optica Sinica 19, 486�??490 (1999).
- B. C. Karamata, P. Lambelet, M. Leutenegger, M. Laubscher, S. Bourquin, and T. Lasser, �??A semi-analytical model accounting for multiple scattering in optical coherence tomography,�?? in Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX , V. V. Tuchin, J. A. Izatt and J. G. Fujimoto, eds. , Proc. SPIE 5690, 386�??396 (2005).
- M. J. C. V. Gemert, S. L. Jacques, H. J. C. M. Sterenborg, and W. M. Star, �??Skin optics,�?? IEEE Trans. Biomed. Eng. 36, 1146�??1154 (1989). [CrossRef] [PubMed]
- L. Wang, S. L. Jacques, and L. Zheng, �??MCML �?? Monte Carlo modeling of light transport in multi-layered tissues,�?? Computer Methods and Programs in Biomedicine 47, 131�??146 (1995). [CrossRef] [PubMed]
- H. J. V. Staveren, C. J. M. Moes, J. V. Marle, S. A. Prahl, and M. J. C. V. Gemert, �??Light scattering in Intralipid-10% in the wavelength range of 400�??1100 nm,�?? Appl. Opt. 30, 4507�??4514 (1991). [CrossRef] [PubMed]
- J. L. Bentley, �??Multidimensional binary search trees used for associative searching,�?? Communications of the ACM 18, 509�??517 (1975). [CrossRef]
Cited By |
OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.





OSA is a member of 