Speckle Reduction in OCT using Massively-Parallel Detection and Frequency-Domain Ranging

doi:10.1364/OE.14.004736

Speckle Reduction in OCT using Massively-Parallel Detection and Frequency-Domain Ranging

A. E. Desjardins, B. J. Vakoc, G. J. Tearney, and B. E. Bouma »View Author Affiliations

Optics Express, Vol. 14, Issue 11, pp. 4736-4745 (2006)
http://dx.doi.org/10.1364/OE.14.004736

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Abstract

Speckle noise significantly limits the information content provided by coherent optical imaging methods such as optical coherence tomography and its recent derivative, optical frequency-domain imaging (OFDI). In this paper, we demonstrate a novel OFDI system that simultaneously acquires hundreds of angularly resolved images, which can be compounded to reduce speckle noise. The system comprises an InGaAs line-scan camera and an interferometer, configured so that the elements of the detector array simultaneously capture light spanning a backscattering angular range of 32 degrees. On successive read-outs of the array, the wavelength of the laser source was stepped through a range of 130 nm centered at 1295 nm to concurrently generate 400 angle-resolved OFDI images. A theory of angle-resolved OFDI and the design equations of the system are presented. Incoherent averaging of the angle-resolved data is shown to yield substantial speckle reduction (as high as an 8 dB SNR improvement) in images of a tissue phantom and esophageal tissue ex vivo.

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 2, 2006
Revised Manuscript: May 9, 2006
Manuscript Accepted: May 15, 2006
Published: May 29, 2006

Virtual Issues
Vol. 1, Iss. 6 Virtual Journal for Biomedical Optics

Citation
A. E. Desjardins, B. J. Vakoc, G. J. Tearney, and B. E. Bouma, "Speckle Reduction in OCT using Massively-Parallel Detection and Frequency-Domain Ranging," Opt. Express 14, 4736-4745 (2006)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-14-11-4736

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References

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